Investigation of mass transfer in vascular endothelial cells by utilizing high-speed confocal PIV techqniue
| Project/Area Number |
25289028
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (B)
|
| Allocation Type | Partial Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Fluid engineering
|
|---|
| Research Institution | Tokyo Institute of Technology (2015)
The University of Tokyo |
|---|
Principal Investigator |
SUGII Yasuhiko 東京工業大学, 理工学研究科, 産学官連携研究員 (90345108)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
MOGI Katsuo 東京工業大学, 理工学研究科, 助教 (20610950)
HISHIDA Koichi 慶應義塾大学, 理工学部, 教授 (40156592)
|
|---|
| Project Period (FY) |
2013-04-01 – 2016-03-31
|
| Project Status |
Completed (Fiscal Year 2015)
|
| Budget Amount *help |
¥18,590,000 (Direct Cost: ¥14,300,000、Indirect Cost: ¥4,290,000)
Fiscal Year 2015: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2014: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2013: ¥8,840,000 (Direct Cost: ¥6,800,000、Indirect Cost: ¥2,040,000)
|
|---|
| Keywords | バイオ流体 / マイクロ流体 / 流体計測 / 共焦点マイクロPIV / 血管内皮細胞 / グリコカリックス / 流体工学 / 超解像度LIF / グリコカリックス層 / 血流 / バイオ流体力学 |
|---|
| Outline of Final Research Achievements |
In order to clarify Glycocalyx layer on vascular endothelial cells, a high resolution measurement technique for three-dimensional velocity distribution was developed by utilizing stealth fluorescent silica particles with a diameter of 100 nm coated with long chains of polyethylene glycol.. The developed technique was applied to endothelial cell cultured in a microfluidic device.
|
Report
(4 results)
Research Products
(14 results)
