| Budget Amount *help |
¥18,070,000 (Direct Cost: ¥13,900,000、Indirect Cost: ¥4,170,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2014: ¥5,980,000 (Direct Cost: ¥4,600,000、Indirect Cost: ¥1,380,000)
Fiscal Year 2013: ¥10,400,000 (Direct Cost: ¥8,000,000、Indirect Cost: ¥2,400,000)
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| Outline of Final Research Achievements |
By large scale analysis of genes selectively expressed in certain area in the primate neocortex, we had reported that such genes could be classified two groups: One is high in the association areas and the other is high in the primary visual cortex. We examined the promoter region of representative association and primary visual area selective genes and found high and low methylation revels,respectively. Furthermore, we found that MBP4, a member of MBPs, can control the association area selective genes of PNMA5 and RBP4 by GOF (gain of function) and LOF (loss of function) analysis.
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