| Budget Amount *help |
¥17,810,000 (Direct Cost: ¥13,700,000、Indirect Cost: ¥4,110,000)
Fiscal Year 2016: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2015: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2014: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2013: ¥8,450,000 (Direct Cost: ¥6,500,000、Indirect Cost: ¥1,950,000)
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| Outline of Final Research Achievements |
The aim of this research project is to establish a culture system that reproduce formation and maintenance of primordial follicles. This project is particularly unique in the point of using pluripotent stem cells, such as embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), as a starting material. Reconstitution of primordial follicle formation/maintenance from plruipotent stem cells would be quite beneficial, as genetic manipulations in the cells are quite feasible. The culture system in this project will contribute to understanding of mechanisms underlying primordial follicle formation/maintenance, which will eventually elucidate causes of infertility.
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