| Budget Amount *help |
¥17,030,000 (Direct Cost: ¥13,100,000、Indirect Cost: ¥3,930,000)
Fiscal Year 2015: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2014: ¥5,720,000 (Direct Cost: ¥4,400,000、Indirect Cost: ¥1,320,000)
Fiscal Year 2013: ¥6,370,000 (Direct Cost: ¥4,900,000、Indirect Cost: ¥1,470,000)
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| Outline of Final Research Achievements |
About 35,000 people every year have died of liver cancer in our country, and treatment for the advanced cancer has not been established yet.
Treatment for the differentiated cancer cells is not enough and it's necessary to understand a peculiar character of a stem cell as the cause of the treatment resistance and the recurrence. In this study, we have made a liver cancer mouse model, established a cell line by a liver cancer 3D culture and analyzed a relationship between epithelial-mesenchymal transition and cancer stemness.
These findings may provide the fundamental materials and technique for development of therapies for cancer stem cells.
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