| Budget Amount *help |
¥18,330,000 (Direct Cost: ¥14,100,000、Indirect Cost: ¥4,230,000)
Fiscal Year 2015: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2014: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2013: ¥8,710,000 (Direct Cost: ¥6,700,000、Indirect Cost: ¥2,010,000)
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| Outline of Final Research Achievements |
For mammalian heart regeneration or repair, we have reported about two factors during heart regeneration to JMCC (Morita et al., 2016a) and DGD (Nakamura et al., 2016). Sall1 which plays as a key factor for cardiac induction (Morita et al., JMCC 2016a) is also re-activated during heart regeneration (Morita et al., submitted 2016b). Baf60c has been identified as a key factor for cardiac formation (Koshiba-Takeuchi et al., Etiology and Morphogenesis of Congenital Heart Disease 2016; Takeuchi & Bruneau. Nature 2009) and also functions for heart regeneration (Nakamura et al., DGD 2016). These results will open the regenerative mechanisms in several organs for the basic science and will give us supportive idea for the heart repair in human.
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