Developmental mechanisms that specify digit identity and patterning
| Project/Area Number |
25291050
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Partial Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Developmental biology
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| Research Institution | Nagoya University |
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Principal Investigator |
Suzuki Takayuki 名古屋大学, 理学(系)研究科(研究院), 講師 (40451629)
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| Co-Investigator(Renkei-kenkyūsha) |
MORISHITA Yoshihiro 理化学研究所QBiC, ユニットリーダー (00404062)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥18,200,000 (Direct Cost: ¥14,000,000、Indirect Cost: ¥4,200,000)
Fiscal Year 2015: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2014: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2013: ¥9,100,000 (Direct Cost: ¥7,000,000、Indirect Cost: ¥2,100,000)
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| Keywords | パターン形成 / 軟骨 / ニワトリ / 形態形成 / 肢芽 / 手足 / ニワトリ胚 / fate map / 階層 / ３次元 / 指形成 / パターン / 発生 / 発生•分化 / 画像解析 / イメージング / 数理生物学 / モデル化 / 定量化 / 遺伝子 |
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| Outline of Final Research Achievements |
Our skeletal pattern is derived from pattern of chondrocyte development. Therefore, studying first developmental step of chondrocyte should give us the most valuable information about positional information of skeletal pattern. In this study, we used chick hindlimb bud as a model system and performed how chondrocyte position is specified in the autopod. We succeeded to establish new quantification method to understand 3-dimentional structure of developing organ, especially limb bud in this study.
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Report
(4 results)
Research Products
(16 results)
