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Designing lighting environments for neonates on the basis of development of visual sensors

Research Project

Project/Area Number 25291110
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypePartial Multi-year Fund
Section一般
Research Field Applied anthropology
Research InstitutionNational Center of Neurology and Psychiatry

Principal Investigator

Ohta Hidenobu  国立研究開発法人国立精神・神経医療研究センター, 精神生理研究部, 研究生 (80422103)

Co-Investigator(Kenkyū-buntansha) 樋口 重和  九州大学, 芸術工学研究科(研究院), 教授 (00292376)
稲垣 真澄  国立研究開発法人国立精神・神経医療研究センター, 精神保健研究所・知的障害研究部, 部長 (70203198)
Co-Investigator(Renkei-kenkyūsha) CHO KAZUTOSHI  北海道大学病院, 周産母子センター, 准教授 (10312365)
Project Period (FY) 2013-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥19,240,000 (Direct Cost: ¥14,800,000、Indirect Cost: ¥4,440,000)
Fiscal Year 2016: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2015: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2014: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2013: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
Keywords早産児 / 正期産児 / メラノプシン / ロドプシン / コーンオプシン / 生理学 / 生理人類学 / 発達生理学 / 環境科学 / 人類生理学 / 光受容体
Outline of Final Research Achievements

Previous studies have demonstrated that a light-dark cycle in the Neonatal Intensive Care Unit (NICU) has promoted better sleep development and weight gain in preterm infants than constant light or constant darkness. However, it was unknown whether exposure to light for brief periods at night for medical treatment and nursing care would compromise the benefits brought about by such a light-dark cycle. To establish the facts to this, we developed a special red LED light with a wavelength of > 675 nm which preterm infants cannot perceive. Preterm infants born at < 36 weeks’ gestational age were randomly assigned for periodic exposure to either white LED light or red LED light at night in a light-dark cycle. Activity, nighttime crying and body weight were continuously monitored from enrolment until discharge.

Report

(4 results)
  • 2016 Final Research Report ( PDF )
  • 2015 Annual Research Report
  • 2014 Annual Research Report
  • 2013 Annual Research Report
  • Research Products

    (27 results)

All 2016 2015 2014 2013 Other

All Journal Article (5 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 3 results,  Open Access: 1 results,  Acknowledgement Compliant: 2 results) Presentation (16 results) (of which Int'l Joint Research: 1 results,  Invited: 11 results) Book (2 results) Remarks (4 results)

  • [Journal Article] Influence of light exposure at nighttime on sleep development and body growth of preterm infants.2016

    • Author(s)
      Kaneshi Y, Ohta H, Morioka K, Hayasaka I, Uzuki Y, Akimoto T, Moriichi A, Nakagawa M, Oishi Y, Wakamatsu H, Honma N, Suma H, Sakashita R, Tsujimura S, Higuchi S, Shimokawara M, Cho K, Minakami H.
    • Journal Title

      Sci Rep.

      Volume: 6 Issue: 1 Pages: 21680-21680

    • DOI

      10.1038/srep21680

    • NAID

      120005743058

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] 管理法はどう変わったか?:温故知新 新生児編.NICUの環境~照度への考え方の変遷.2014

    • Author(s)
      兼次洋介,中川真智子, 李こう,太田英伸.
    • Journal Title

      周産期医学

      Volume: 44 Pages: 527-532

    • Related Report
      2014 Annual Research Report
    • Acknowledgement Compliant
  • [Journal Article] Controllable Light Filters Using an All-Solid-State Switchable Mirror with a Mg-Ir Thin Film for Preterm Infant Incubators.2013

    • Author(s)
      Tajima K, Shimoike M, Li H, Inagaki M, Izumi H, Akiyama M, Matsushima Y, Ohta H
    • Journal Title

      Appl Phys Lett

      Volume: 102 Issue: 16 Pages: 1619131-1619134

    • DOI

      10.1063/1.4801848

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Designing artificial environments for preterm infants based on circadian studies on pregnant uterus.2013

    • Author(s)
      Watanabe S, Akiyama S, Hanita T, Li H, Nakagawa M, Kaneshi Y, Ohta H, Japan RED filter study group
    • Journal Title

      Front Endocrinol

      Volume: 4 Pages: 1131-11311

    • DOI

      10.3389/fendo.2013.00113

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 人工保育器向け調光型フィルターの開発.2013

    • Author(s)
      田嶌一樹,李 コウ,太田英伸
    • Journal Title

      光アライアンス

      Volume: 11 Pages: 30-34

    • Related Report
      2013 Annual Research Report
  • [Presentation] 視覚環境から考えた赤ちゃんにやさしいケア2016

    • Author(s)
      太田英伸
    • Organizer
      日本視覚学会2016年冬季大会
    • Place of Presentation
      工学院大学新宿キャンパス
    • Year and Date
      2016-01-21
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] 発達期の恒明光環境が成長後のマウス体内時計機能に与える可塑的な影響2015

    • Author(s)
      井上莉香, 竹生田淳, 沢内美穂, 鈴木登紀子, 太田英伸, 守屋孝洋.
    • Organizer
      第22回日本時間生物学会学術大会
    • Place of Presentation
      東京大学伊藤国際学術研究センター
    • Year and Date
      2015-11-21
    • Related Report
      2015 Annual Research Report
  • [Presentation] Lighting conditions and developing human biological clocks2015

    • Author(s)
      Hidenobu Ohta
    • Organizer
      International Congress of Physiological Anthropology 2015
    • Place of Presentation
      Tokyo Bay Makuhari Hall
    • Year and Date
      2015-10-28
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 保育環境から考えた赤ちゃんにやさしいケア~光環境の視点から~2015

    • Author(s)
      太田英伸
    • Organizer
      第10回Neonatal Care Forum in Tokyo Metropolitan Area
    • Place of Presentation
      大宮ソニックシティ
    • Year and Date
      2015-09-26
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] 赤ちゃんは光を発達にどのように利用するか?2015

    • Author(s)
      太田英伸
    • Organizer
      第3回発達保育実践政策学セミナー
    • Place of Presentation
      東京大学教育学部
    • Year and Date
      2015-06-17
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] 新生児室における夜間の光環境デザイン.2015

    • Author(s)
      太田英伸, 兼次洋介,森岡圭太,早坂 格,夘月ゆたか,秋元琢真,盛一享徳,中川真智子,大石芳久,樋口重和,安積陽子,高橋紀子,中澤貴代,本間直樹,須摩弘樹,坂下隆一,下河原みゆき,長 和俊,水上尚典.
    • Organizer
      第72回日本生理人類学会大会
    • Place of Presentation
      北海道大学医学部
    • Year and Date
      2015-05-30
    • Related Report
      2015 Annual Research Report
  • [Presentation] 光フィルター保育器の研究開発と実用化.2014

    • Author(s)
      太田英伸
    • Organizer
      第21回日本時間生物学会学術大会
    • Place of Presentation
      九州大学医学部百年講堂、福岡
    • Year and Date
      2014-11-09
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 胎児・新生児の神経系の発達とディベロップメンタル・ケア~大脳皮質の発達.2014

    • Author(s)
      太田英伸
    • Organizer
      第11回ディベロップメンタルケアセミナー
    • Place of Presentation
      三宮研修センター、兵庫県三宮市
    • Year and Date
      2014-10-25
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 早産児の光環境と睡眠.2014

    • Author(s)
      太田英伸
    • Organizer
      埼玉医科大学医学部・神経科学セミナー
    • Place of Presentation
      埼玉医科大学医学部、埼玉県日高市
    • Year and Date
      2014-10-08
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Melanopsin and visual development of neonates.2014

    • Author(s)
      Hidenobu Ohta
    • Organizer
      Seminar in Neuroscience Program
    • Place of Presentation
      Vanderbilt University, Nashiville, USA
    • Year and Date
      2014-09-25
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Lighting conditions and developing biological clocks.2014

    • Author(s)
      Hidenobu Ohta
    • Organizer
      Seminar in Department of Biological Sciences
    • Place of Presentation
      Vanderbilt University, Nashiville, USA
    • Year and Date
      2014-09-22
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 胎児・新生児の神経系の発達とディベロップメンタル・ケア~大脳皮質の発達.2014

    • Author(s)
      太田英伸
    • Organizer
      第10回ディベロップメンタルケアセミナー
    • Place of Presentation
      平成帝京大学、東京
    • Year and Date
      2014-07-26
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 早産児の光環境と睡眠.2014

    • Author(s)
      太田英伸, 中川真智子, 兼次洋介, 李コウ, Japan RED filter study group
    • Organizer
      第56回日本小児神経学会学術集会
    • Place of Presentation
      アクトシティ浜松、浜松市
    • Year and Date
      2014-05-30
    • Related Report
      2014 Annual Research Report
  • [Presentation] 胎児・新生児の神経系の発達とディベロップメンタル・ケア~大脳皮質の発達.2013

    • Author(s)
      太田英伸
    • Organizer
      第8回ディベロップメンタルケアセミナー
    • Place of Presentation
      東京 墨東病院
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] ヒト光受容体の発達と早産児の睡眠.2013

    • Author(s)
      太田英伸,渡辺真平,秋山志津子,埴田卓志,李 コウ,Japan RED filter study group
    • Organizer
      日本睡眠学会第38回定期学術集会
    • Place of Presentation
      秋田 秋田キャッスルホテル
    • Related Report
      2013 Annual Research Report
  • [Presentation] 光フィルターによる早産児の人工保育環境の設計.2013

    • Author(s)
      太田英伸,守屋孝洋,飯郷雅之,Japan RED filter study group
    • Organizer
      第20回日本時間生物学会学術大会
    • Place of Presentation
      大阪 近畿大学
    • Related Report
      2013 Annual Research Report
  • [Book] 標準ディベロップメンタルケア2014

    • Author(s)
      日本ディベッロップメンタルケア(DC)研究会・仁志田博司ら編
    • Total Pages
      306
    • Publisher
      メディカ出版
    • Related Report
      2014 Annual Research Report
  • [Book] おなかの赤ちゃんは光を感じるか―生物時計とメラノプシン2014

    • Author(s)
      太田英伸
    • Total Pages
      122
    • Publisher
      岩波書店
    • Related Report
      2014 Annual Research Report
  • [Remarks] researchmap

    • URL

      http://researchmap.jp/read001326/

    • Related Report
      2015 Annual Research Report
  • [Remarks] 国立精神・神経研究開発センター 精神保健研究所 知的障害研究部 診断研究室

    • URL

      http://www.ncnp.go.jp/nimh/chiteki/laboratory/ota.html

    • Related Report
      2014 Annual Research Report
  • [Remarks] Researchmap

    • URL

      http://researchmap.jp/read001326/

    • Related Report
      2014 Annual Research Report
  • [Remarks] http://www.ncnp.go.jp/nimh/chiteki/index.html

    • Related Report
      2013 Annual Research Report

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Published: 2013-05-21   Modified: 2023-03-23  

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