| Budget Amount *help |
¥18,460,000 (Direct Cost: ¥14,200,000、Indirect Cost: ¥4,260,000)
Fiscal Year 2016: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2015: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2014: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2013: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
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| Outline of Final Research Achievements |
We developed the model system for evasion of Ralstonia solanacearum-induced innate immunity by Nicotiana benthamiana and elucidate jasmonic acid-mediated innate immunity used phosphatidic acid as a substrate. It was required for several effectors secreted by R. solanacearum to induce expression of phosphatidic acid phosphatase gene in N. benthamiana, evading its innate immunity. This innate immunity was induced by infection with other plant bacteria such as Pseudomonas syringae. These bacteria also secrete effectors through the type III secretion machinery to induce expression of phosphatidic acid phosphatase gene, evading innate immunity by N. benthamiana. After evading innate immunity, virulent strain OE1-1 of R. solanacearum grew on host cells and produced mushroom-type biofilms which was required for its virulence. Taken together, these results open the door to uncover key interactions between host plants and R. solanacearum at the initial stage of infection.
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