New approaches towards high-value added lignin production by the combination of metabolic engineering and organic chemistry
| Project/Area Number |
25292104
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Partial Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Wood science
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| Research Institution | Kyoto University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
SUZUKI Shiro 京都大学, 生存圏研究所, 助教 (70437268)
TOBIMATSU Yuki 京都大学, 生存圏研究所, 准教授 (20734221)
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| Co-Investigator(Renkei-kenkyūsha) |
SHIBATA Daisuke かずさDNA研究所, 部長 (10370925)
SUZUKI Hideyuki かずさDNA研究所, 主任研究員 (80276162)
KAWAMOTO Haruo 京都大学, 大学院エネルギー科学研究科, 准教授 (80224864)
KIKUCHI Jun 理化学研究所, 先端NMRメタボロミクスチーム, チームリーダー (00321753)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥18,070,000 (Direct Cost: ¥13,900,000、Indirect Cost: ¥4,170,000)
Fiscal Year 2015: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2014: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2013: ¥11,310,000 (Direct Cost: ¥8,700,000、Indirect Cost: ¥2,610,000)
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| Keywords | リグニン / 代謝工学 / 有機化学 / イネ科植物 / 還元分解 / 芳香核構造単純化 / 有機工業原材料 / 芳香族資源 |
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| Outline of Final Research Achievements |
Towards development of technologies for sustainable utilization of renewable lignocellulose biomass, development of high-value added products from lignin is critically important. To do so, simplification of lignin structures are of fundamental importance. Herein, we developed a new reductive reaction to decrease the complexity of lignin aromatic composition. In addition, we engineered lignin biosynthesis in rice to give rise to transgenic rice plants where aromatic composition of lignins was largely simplified yielding lignins composed mainly of p-hydroxyphenyl, guaiacyl or syringyl units. New findings on reactivity of the engineered ligninocelluloses was also obtained. Taken together, this study provided basic knowledges for future lignocellulose utilization.
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Report
(4 results)
Research Products
(34 results)
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[Presentation] CAD2 deficiency causes both brown midrib and gold hull and internode phenotypes in Oryza sativa2014
Author(s)
Taichi Koshiba, Shinya Murakami, Takefumi Hattori, Mai Mukai, Akira Takahashi, Akio Miyao, Hirohiko Hirochika, Shiro Suzuki, Masahiro Sakamoto, Toshiaki Umezawa
Organizer
53rd Annual Meeting of the Phytochemical Society of North America (PSNA 2014)
Place of Presentation
Raleigh, USA
Year and Date
2014-08-09 – 2014-08-13
Related Report
Invited
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