| Budget Amount *help |
¥18,590,000 (Direct Cost: ¥14,300,000、Indirect Cost: ¥4,290,000)
Fiscal Year 2016: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2015: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2014: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2013: ¥6,890,000 (Direct Cost: ¥5,300,000、Indirect Cost: ¥1,590,000)
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| Outline of Final Research Achievements |
We studied the improving effect of brain function by “phycoerythlin (PE)” from the red alga dulse (Palmaria palmata) using the senescence-accelerated mouse prone-10 (SAMP10). It was clarified that dulse PE shows antioxidative effect and the active factor is its chromophore. Then, by long-term administration of dulse PE to SAMP10, the deterioration of circadian rhythm depending on aging of SAMP10 was significantly restrained. In addition, the spatial perception of SAMP10 was significantly maintained by long-term administration of dulse PE. It was thought that these effects were derived from a reduction of oxidative stress in SAMP10 by dulse PE.
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