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Elucidation of biological functions through the water by Aquaphotomics

Research Project

Project/Area Number 25292156
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypePartial Multi-year Fund
Section一般
Research Field Agricultural environmental engineering/Agricultural information engineering
Research InstitutionKobe University

Principal Investigator

Tsenkova Roumiana  神戸大学, (連合)農学研究科(研究院), 教授 (30294200)

Co-Investigator(Kenkyū-buntansha) OMIDO Nobuko  神戸大学, 人間発達環境学, 教授 (30343263)
Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥15,210,000 (Direct Cost: ¥11,700,000、Indirect Cost: ¥3,510,000)
Fiscal Year 2015: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2014: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2013: ¥6,630,000 (Direct Cost: ¥5,100,000、Indirect Cost: ¥1,530,000)
Keywordsaquaphotomics / NIRS / cells / probiotics / water / Aquaphotomics / water species / functionality of water / somatic rice cell / callus rice cell / probiotic Lactobacillus / cell development / NIR spectroscopy
Outline of Final Research Achievements

The main objective all over our research is to achieve more information about the roles of water molecular network in different leaving cells through the lens of NIR light using Aquaphotomics approach.Lactobacillus bacteria strains grown in liquid cultures and different plant cells were studied.Water spectral pattern has been successfully used as biomarker for plant cell identification, monitoring of developmental stages of plant and bacteria cells and for monitoring and identification of bacteria.
As the primary goal of this project we proved with experimental results that the concept of Aquaphotomics provide the opportunity to develop tools including spectrophotometer and data analysis methods and software to precisely identify specific water bands, which can be used as water matrix coordinates of spectral patterns to be further used as biomarkers.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Annual Research Report
  • 2013 Annual Research Report
  • Research Products

    (47 results)

All 2016 2015 2014 Other

All Int'l Joint Research (2 results) Journal Article (11 results) (of which Int'l Joint Research: 7 results,  Peer Reviewed: 8 results,  Open Access: 7 results,  Acknowledgement Compliant: 3 results) Presentation (31 results) (of which Int'l Joint Research: 4 results,  Invited: 2 results) Book (2 results) Remarks (1 results)

  • [Int'l Joint Research] 食品技術大学/トラキア大学(ブルガリア)

    • Related Report
      2015 Annual Research Report
  • [Int'l Joint Research] ベオグラード大学(セルビア)

    • Related Report
      2015 Annual Research Report
  • [Journal Article] Evaluating spectral signals to identify spectral error2016

    • Author(s)
      Bazar G, Kovacs Z, Tsenkova R
    • Journal Title

      PLOS ONE

      Volume: 11 Issue: 1 Pages: 1-15

    • DOI

      10.1371/journal.pone.0146249

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Water spectral pattern as holistic marker for water quality monitoring2016

    • Author(s)
      Kovacs Z, Bazar G, Oshima M, Shigeoka S, Tanaka M, Furukawa A, Nagaia A, Osawa M, Itakura Y, Tsenkova R
    • Journal Title

      TALANTA

      Volume: 147 Pages: 598-608

    • DOI

      10.1016/j.talanta.2015.10.024

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Monitoring of water spectral pattern reveals differences in probiotics growth when used for rapid bacteria selection2015

    • Author(s)
      Slavchev A, Kovacs Z, Koshiba H, Nagai A, Bazar G, Krastanov A, Kubota Y, Tsenkova R
    • Journal Title

      PLOS ONE

      Volume: 10 Issue: 7 Pages: 1-18

    • DOI

      10.1371/journal.pone.0130698

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Water revealed as molecular mirror when measuring low concentrations of sugar with near infrared light2015

    • Author(s)
      Bazar G, Kovacs Z, Tanaka M, Furukawa A, Nagai A, Osawa M, Itakura Y, Sugiyama H, Tsenkova R
    • Journal Title

      ANALYTICA CHIMICA ACTA

      Volume: 896 Pages: 52-62

    • DOI

      10.1016/j.aca.2015.09.014

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Detection of UV-induced cyclobutane pyrimidine dimers by near-infrared spectroscopy and aquaphotomics2015

    • Author(s)
      Goto N, Bazar C, Kovacs Z, Kunisada M, Morita H, Kizaki S, Sugiyama H, Tsenkova R, Nishigori C
    • Journal Title

      Sci Rep

      Volume: Jul 2;5 Issue: 1 Pages: 11808-11808

    • DOI

      10.1038/srep11808

    • NAID

      120005822771

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Aquagrams of raw milk for estrus detection in dairy cows - short communication2015

    • Author(s)
      Takemura G, Bazar G, Ikuta K, Yamaguchi E, Ishikawa S, Furukawa A, Kubota Y, Kovacs Z, Tsenkova R
    • Journal Title

      REPRODUCTION IN DOMESTIC ANIMALS

      Volume: 50 Pages: 522-525

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Easy and rapid screening of probiotic strains2015

    • Author(s)
      Koshiba H, Slavchev A, Kovacs Z, Kubota Y, Tsenkova R
    • Journal Title

      JOURNAL OF THE JAPANESE SOCIETY OF AGRICULTURAL MACHINARY AND FOOD ENGINEERS

      Volume: 77 Pages: 146-150

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Aquagrams of raw milk for estrus detection in dairy cows2015

    • Author(s)
      Go Takemura, Gyorgy Bazar, Kentarou Ikuta, Etsuji Yamaguchi, Shou Ishikawa, Akane Furukawa, Yosuke Kubota, Zoltan Kovacs, Roumiana Tsenkova
    • Journal Title

      Reproduction in Domestic Animals

      Volume: 50 Issue: 3 Pages: 522-525

    • DOI

      10.1111/rda.12504

    • Related Report
      2014 Annual Research Report
    • Open Access
  • [Journal Article] プロバイオティクス菌株の簡易かつ迅速な選定方法の開発2014

    • Author(s)
      Haruki Koshiba、Aleksandar Slavchev,Zoltan Kovacs,Yosuke Kubota, Roumiana Tsenkova
    • Journal Title

      農業食料工学会誌

      Volume: 77 Pages: 146-150

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Chromosome Interior Observation byFocused Ion Beam/Scanning Electron Microscopy (FIB/SEM) Using Ionic Liquid Technique.2014

    • Author(s)
      Hamano T, Dwiranti A, Kaneyoshi K, Fukuda S, Kometani R, Nakao M,
    • Journal Title

      Microsc Microanal.

      Volume: 10 Pages: 1-8

    • Related Report
      2014 Annual Research Report
  • [Journal Article] Cell differentiation and development in Arabidopsis are associated with changes in histone dynamics at the single cell level.2014

    • Author(s)
      Stefanie Rosa, Vardis Ntoukakis, Nobuko Ohmido, Alison Pendle, Rita Abranches, Peter Shaw
    • Journal Title

      Plant cell

      Volume: 26 Pages: 4821-4833

    • Related Report
      2014 Annual Research Report
  • [Presentation] Discovering the rules of water in biology using Aquaphotomics2016

    • Author(s)
      Kovacs Z
    • Organizer
      International Symposium on Aquaphotomics: Water Spectroscopy and Quantum Electrodynamics in Biology.
    • Place of Presentation
      神戸大学
    • Year and Date
      2016-03-11
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] アミロイド線維の伝播核形成過程における水の関与性2015

    • Author(s)
      茶谷絵理、平松貴人、板倉由佳利、増田裕輝、ツェンコヴァ ルミアナ
    • Organizer
      BMB 2015
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2015-12-01
    • Related Report
      2015 Annual Research Report
  • [Presentation] 近赤外分光法及びアクアフォトミクスによるアミロイド線維核形成の早期検出2015

    • Author(s)
      平松貴人、板倉由佳利、茶谷絵理、ツェンコヴァ ルミアナ
    • Organizer
      BMB 2015
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2015-12-01
    • Related Report
      2015 Annual Research Report
  • [Presentation] 近赤外分光法を用いたアミロイド線維形成過程における塩の影響に関する研究2015

    • Author(s)
      板倉由佳利、平松貴人、茶谷絵理、ツェンコヴァ ルミアナ
    • Organizer
      第31回近赤外フォーラム
    • Place of Presentation
      筑波大学
    • Year and Date
      2015-11-27
    • Related Report
      2015 Annual Research Report
  • [Presentation] フィルターペーパーを用いた近赤外分光法によるボルネオオランウータン(Pongo Pygmaeus)の尿中エストロゲン代謝産物濃度測定について2015

    • Author(s)
      ツェンコヴァ ルミアナ
    • Organizer
      第31回近赤外フォーラム
    • Place of Presentation
      筑波大学
    • Year and Date
      2015-11-26
    • Related Report
      2015 Annual Research Report
  • [Presentation] 生乳のスペクトルデータを用いた乳牛の発情診断システムの開発2015

    • Author(s)
      石川翔 、生田健太郎、窪田陽介、ツェンコヴァ ルミアナ
    • Organizer
      農業環境工学関連学会2015年合同大会、農業食料工学会
    • Place of Presentation
      岩手大学
    • Year and Date
      2015-11-26
    • Related Report
      2015 Annual Research Report
  • [Presentation] アミロイド線維の核形成におけるタンパク質および水の動態解明2015

    • Author(s)
      平松貴人、茶谷絵理、ツェンコヴァ ルミアナ
    • Organizer
      第31回近赤外フォーラム
    • Place of Presentation
      筑波大学
    • Year and Date
      2015-11-25
    • Related Report
      2015 Annual Research Report
  • [Presentation] Near Infrared Spectroscopy in biological systems2015

    • Author(s)
      Tsenkova R
    • Organizer
      International Post Graduate Course
    • Place of Presentation
      Santiago, Argentine
    • Year and Date
      2015-11-02
    • Related Report
      2015 Annual Research Report
  • [Presentation] Aquaphotomics: Near infrared spectroscopy and water states in Biological systems2015

    • Author(s)
      Tsenkova R
    • Organizer
      SAB Annual Meeting
    • Place of Presentation
      Santiago, Argentine
    • Year and Date
      2015-11-02
    • Related Report
      2015 Annual Research Report
  • [Presentation] Near Infrared Spectroscopy and Aquaphotomics for non-invasive cell identification and diagnosis2015

    • Author(s)
      ツェンコヴァ ルミアナ
    • Organizer
      第67回 日本生物工学会大会
    • Place of Presentation
      鹿児島 城山観光ホテル
    • Year and Date
      2015-10-27
    • Related Report
      2015 Annual Research Report
  • [Presentation] Aquaphotomics:Water spectral pattern reveals UV induced changes of DNA and identifies bacteria functionality2015

    • Author(s)
      Tsenkova R
    • Organizer
      Physics, Chemistry and Biology of Water
    • Place of Presentation
      Bulgaria
    • Year and Date
      2015-10-01
    • Related Report
      2015 Annual Research Report
  • [Presentation] Water not only a solvent but also a mirror2015

    • Author(s)
      Tsenkova R
    • Organizer
      Italian Physics Society
    • Place of Presentation
      Napoli, Italy
    • Year and Date
      2015-09-29
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Aquaphotomics-radically new scientific platform for bio-and food technology2015

    • Author(s)
      Tsenkova R
    • Organizer
      Aquaphotomics at CREA-FLC
    • Place of Presentation
      Lodi, Italy
    • Year and Date
      2015-09-25
    • Related Report
      2015 Annual Research Report
  • [Presentation] Aquaphotomics : Water spectral pattern as molecular mirror2015

    • Author(s)
      Tsenkova R
    • Organizer
      EXPO 2015 NIR seminar in cooperation with ChemMed
    • Place of Presentation
      Milano, Italy
    • Year and Date
      2015-09-24
    • Related Report
      2015 Annual Research Report
  • [Presentation] Aquaphotomics : Water special pattern as molecular mirror2015

    • Author(s)
      Tsenkova R
    • Organizer
      Bulgarian Academy of Sciencies, The Institute of Polymers
    • Place of Presentation
      Sophia, Bulgaria
    • Year and Date
      2015-09-17
    • Related Report
      2015 Annual Research Report
  • [Presentation] 近赤外スペクトルを用いた生乳の鮮度評価法の開発2015

    • Author(s)
      大澤真奈美 、窪田陽介、 生田健太郎、ツェンコヴァ ルミアナ
    • Organizer
      農業環境工学関連5学会
    • Place of Presentation
      岩手大学
    • Year and Date
      2015-09-15
    • Related Report
      2015 Annual Research Report
  • [Presentation] 近赤外分光法を用いたアミロイド線維形成過程における構造変化の解明2015

    • Author(s)
      板倉由佳利、平松貴人、茶谷絵理、ツェンコヴァ ルミアナ
    • Organizer
      農業環境工学関連5学会
    • Place of Presentation
      岩手大学
    • Year and Date
      2015-09-15
    • Related Report
      2015 Annual Research Report
  • [Presentation] Aquqphotomics leading to disease diagnosis and understanding2015

    • Author(s)
      Tsenkova R
    • Organizer
      Bulgarian Medical Academy of Science
    • Place of Presentation
      Sophia, Bulgaria
    • Year and Date
      2015-09-14
    • Related Report
      2015 Annual Research Report
  • [Presentation] Water revealed as molecular mirror when measuring low concentrations of sugar with near infrared light2015

    • Author(s)
      Kovacs Z
    • Organizer
      International Symposium on Recent Advanced in Near Infrared Spectroscopy
    • Place of Presentation
      兵庫県三田市
    • Year and Date
      2015-09-05
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 近赤外分光法を用いたボルネオオランウータン(Pongo Pygmaeus)の尿中エストロゲン代謝産物とクレアチニン濃度測定について2015

    • Author(s)
      木下こづえ、ツェンコヴァ ルミアナ
    • Organizer
      第31回日本霊長類学会大会
    • Place of Presentation
      京都大学
    • Year and Date
      2015-08-30
    • Related Report
      2015 Annual Research Report
  • [Presentation] Water spectral pattern of raw milk for oestrus detection in dairy cows2015

    • Author(s)
      Tsenkova R, Kovacs Z, Bazar G, Kubota Y
    • Organizer
      Controversies & Consensus in Bovine Health, Industry & Economics (CoBo)
    • Place of Presentation
      Berlin
    • Year and Date
      2015-08-27
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Aquaphotomics を利用した近赤外線分光法によるCPD形成の定量的計測の試み2015

    • Author(s)
      後藤典子、バザール ジョージ、コバチ ゾルタン、ツェンコヴァ ルミアナ
    • Organizer
      第37回日本光医学・光生物学会
    • Place of Presentation
      宮崎シーガイアコンベンションセンター
    • Year and Date
      2015-07-17
    • Related Report
      2015 Annual Research Report
  • [Presentation] Camellia属植物および種間雑種におけるrDNA配列FISHの比較2015

    • Author(s)
      古川一実、飯田誠也, 寺前香里, 小川桜子, 近江戸伸子
    • Organizer
      育種学会
    • Place of Presentation
      玉川大学
    • Year and Date
      2015-03-21 – 2015-03-22
    • Related Report
      2014 Annual Research Report
  • [Presentation] Research of early flowering transgenic Jatropha plant2015

    • Author(s)
      Ayaka Hata,Suguru Tsuchimoto, Kiichi Fukui, Hisashi Tomemori, Hisashi Tsujimoto, Nobuko Ohmido
    • Organizer
      8th International Symposium Exploring the global sustainability-Advances in Plant Biotechnology for Agriculture in Semi-ariland
    • Place of Presentation
      大阪大学
    • Year and Date
      2015-03-03 – 2015-03-04
    • Related Report
      2014 Annual Research Report
  • [Presentation] Assesment of tolerance of genus Lactobacillus strains to human digestive fluids using NIRS and Aquaphotomics.2014

    • Author(s)
      Haruki Koshiba, Aleksandar Slavchev, Zoltan Kovacs, Airi Nagai, Roumiana Tsenkova
    • Organizer
      30th NIR forum (held under Japan Council for Near Infrared Spectroscopy (JNIRS)
    • Place of Presentation
      University of Tsukuba, Tsukuba city, Ibaraki prefecture
    • Year and Date
      2014-11-26 – 2014-11-28
    • Related Report
      2014 Annual Research Report
  • [Presentation] 系統的に異なるSpinacia属植物からの同型および異型性染色体の同定2014

    • Author(s)
      藤戸聡史、鈴木 伶実、星野 洋一郎、近江戸 伸子、小野寺 康之
    • Organizer
      分子生物学会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-11-25 – 2014-11-27
    • Related Report
      2014 Annual Research Report
  • [Presentation] Demonstrations of new tools for spectral data analysis & NIRS of Waters. Aquaphotomics: Understanding Water in the Biological World2014

    • Author(s)
      Bernhard Pollner, Zoltan Kovacs
    • Organizer
      5th Kobe University Brussels European Center Symposium
    • Place of Presentation
      Brussels, Belgium
    • Year and Date
      2014-10-14
    • Related Report
      2014 Annual Research Report
  • [Presentation] Near Infrared Spectroscopy (NIRS) and Aquaphotomics for Understanding Probiotic Lactic Acid Bacteria (LAB)2014

    • Author(s)
      Haruki Koshiba, Aleksandar Slavchev, Zoltan Kovacs, Airi Nagai, Roumiana Tsenkova
    • Organizer
      International Diffuse Reflectance Conference
    • Place of Presentation
      Chambersburg, Pennsylvania, USA
    • Year and Date
      2014-08-02 – 2014-08-08
    • Related Report
      2014 Annual Research Report
  • [Presentation] Evaluation of spectral signal in order to identify possible spectral error. Near Infrared Spectroscopy (NIRS) and Aquaphotomics for Understanding Probiotic Lactic Acid Bacteria (LAB)2014

    • Author(s)
      George Bazar, Zoltan Kovacs, Roumiana Tsenkokva
    • Organizer
      International Diffuse Reflectance Conference
    • Place of Presentation
      Chambersburg, Pennsylvania, USA
    • Year and Date
      2014-08-02 – 2014-08-08
    • Related Report
      2014 Annual Research Report
  • [Presentation] Monitoring of the development of somatic and callus rice cells using Aquaphotomics2014

    • Author(s)
      -Zoltan Kovacs, Nobuko Ohmido, Gyorgy Bazar, Roumiana Tsenkova
    • Organizer
      農業食料工学会
    • Place of Presentation
      琉球大学、Okinawa, Japan
    • Year and Date
      2014-05-16 – 2014-05-19
    • Related Report
      2014 Annual Research Report
  • [Presentation] Identification of probiotic bacteria by Aquaphotomics2014

    • Author(s)
      -Haruki Koshiba, Zoltan Kovacs, Aleksandar Slavchev, Roumiana Tsenkova
    • Organizer
      農業食料工学会
    • Place of Presentation
      琉球大学、Okinawa, Japan
    • Year and Date
      2014-05-16 – 2014-05-19
    • Related Report
      2014 Annual Research Report
  • [Book] Aquaphotomics: Near Infrared Spectroscopy and Water States in Biological Systems In: Disalvo E Anibal (Editor) Membrane Hydration2015

    • Author(s)
      Tsenkova R, Kovacs Z, Kubota Y
    • Publisher
      Springer International Publishing
    • Related Report
      2015 Annual Research Report
  • [Book] Plant Image Analysis: Fundamentals and Applications. Advances in Imaging Methods on Plant Chromosomes.2014

    • Author(s)
      Toshiyuki Wako, Seiji Kato, Nobuko Ohmido and Kiichi Fukui
    • Total Pages
      30
    • Publisher
      CRC Press
    • Related Report
      2014 Annual Research Report
  • [Remarks] 神戸大学農学研究科生体計測工学研究室HP

    • URL

      http://nirslab.org/index_ja.html

    • Related Report
      2015 Annual Research Report

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Published: 2013-05-21   Modified: 2022-02-01  

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