| Budget Amount *help |
¥19,110,000 (Direct Cost: ¥14,700,000、Indirect Cost: ¥4,410,000)
Fiscal Year 2016: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2015: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2014: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2013: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
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| Outline of Final Research Achievements |
In this project, we aimed to explore the mechanisms of actions of adipocyte-derived cytokine (adipocytokine), which is recognized as one of the possible mediators responsible for the visceral obesity-induced cardiovascular diseases including atherosclerosis. We have clarified the novel cardiovascular effects and mechanisms exerted by adipocytokines. We also succeeded in classifying adipocytokines into good and bad type. Based on the present findings and further investigations, it is expected that adipocytokines might be applicable to the diagnosis, prevention and treatment for metabolic cardiovascular diseases.
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