| Project/Area Number |
25293138
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (B)
|
| Allocation Type | Partial Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Epidemiology and preventive medicine
|
|---|
| Research Institution | Yamagata University |
|---|
Principal Investigator |
Kawasaki Ryo 山形大学, 医学(系)研究科(研究院), 准教授 (70301067)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
OIZUMI Toshihide 山形大学, 大学院医学系研究科, 講師 (00344797)
DAIMON Makoto 弘前大学, 大学院医学系研究科, 教授 (20241698)
KONTA Tsuneo 山形大学, 医学部, 准教授 (60333952)
SHIBATA Yoko 山形大学, 医学部, 講師 (60333978)
|
|---|
| Project Period (FY) |
2013-04-01 – 2016-03-31
|
| Project Status |
Completed (Fiscal Year 2015)
|
| Budget Amount *help |
¥17,680,000 (Direct Cost: ¥13,600,000、Indirect Cost: ¥4,080,000)
Fiscal Year 2015: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2014: ¥5,590,000 (Direct Cost: ¥4,300,000、Indirect Cost: ¥1,290,000)
Fiscal Year 2013: ¥7,280,000 (Direct Cost: ¥5,600,000、Indirect Cost: ¥1,680,000)
|
|---|
| Keywords | 予防医学 / 疫学 / 循環器 / 網膜 / 循環器高血圧 / 糖尿病 / 呼吸器疾患 |
|---|
| Outline of Final Research Achievements |
Background: Retinal vasculature is unique “window” where vessels can be observed in vivo. Retinal vascular signs have been utilized as a marker to indicate risk of hypertension and arteriolosclerosis. However, there was an issue that inter-rater agreement is not good; thus, quantitative markers have been warranted. Aim: We studies whether newer markers of retinal vasculature by quantifying retinal morphological features. Results: We found that the presence of retinal vascular diseases was associated with higher risk of stroke. Retinal vascular calibre was associated with smoking sensitivity related to deterioration in male smokers, risk of micro-albuminuria, and insulin resistance all associated with the further risk of cardiovascular diseases.
|
