• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Analytic epidemiology about protection against influenza among infants under 6 months of age

Research Project

Project/Area Number 25293152
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypePartial Multi-year Fund
Section一般
Research Field Hygiene and public health
Research InstitutionOsaka City University

Principal Investigator

OHFUJI Satoko  大阪市立大学, 大学院医学研究科, 准教授 (70433290)

Co-Investigator(Kenkyū-buntansha) FUKUSHIMA Wakaba  大阪市立大学, 大学院医学研究科, 教授 (70420734)
KONDO Kyoko  大阪市立大学, 医学部・附属病院運営本部, 技術職員 (80420727)
MAEDA Akiko  大阪市立大学, 大学院医学研究科, 研究員 (40250279)
Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥7,540,000 (Direct Cost: ¥5,800,000、Indirect Cost: ¥1,740,000)
Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2014: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2013: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Keywords感染症 / インフルエンザ / 乳児 / 疫学 / ワクチン有効性
Outline of Final Research Achievements

To examine the effectiveness of maternal influenza vaccination on preventing influenza in infants under 6 months of age, we conducted a cohort study among 4,068 infants born before 2013/14 influenza season in Osaka. During 2013/14 season, a total of 85 infants (2%) were diagnosed with influenza and 19 infants (0.5%) were hospitalized with influenza. Maternal influenza vaccination (especially prenatal vaccination) revealed to have a decreasing effect on infants' influenza. Vaccine effectiveness of prenatal vaccination was 60% (95% confidence interval: 13%-82%), whereas that of postpartum vaccination was 48% (-41-81%). Although maternal influenza vaccination was also associated with decreasing infants' influenza-related hospitalization, vaccine effectiveness (70%) could not reach to the statistically significance due to limited number of hospitalized cases.
Present findings indicated that pregnant women should receive influenza vaccination in order to protect their infants.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Annual Research Report
  • 2013 Annual Research Report
  • Research Products

    (1 results)

All 2013

All Journal Article (1 results)

  • [Journal Article] 特集 クローズアップインフルエンザ、各論 インフルエンザワクチンの有効性.2013

    • Author(s)
      大藤さとこ、廣田良夫
    • Journal Title

      小児内科

      Volume: 45 Pages: 2005-2008

    • Related Report
      2013 Annual Research Report

URL: 

Published: 2013-05-21   Modified: 2019-07-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi