| Co-Investigator(Kenkyū-buntansha) |
MIZUKI Nobuhisa 横浜市立大学, 医学研究科, 教授 (90336579)
HIRAWA Nobuhito 横浜市立大学, 市民総合医療センター, 准教授 (20315766)
OKA Akira 東海大学, 付置研究所, 講師 (80384866)
YATSU Keisuke 横浜市立大学, 附属病院, 助教 (10457856)
KOBAYASHI Yusuke 横浜市立大学, 医学研究科, 客員研究員 (60612629)
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| Budget Amount *help |
¥18,330,000 (Direct Cost: ¥14,100,000、Indirect Cost: ¥4,230,000)
Fiscal Year 2015: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2014: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2013: ¥10,010,000 (Direct Cost: ¥7,700,000、Indirect Cost: ¥2,310,000)
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| Outline of Final Research Achievements |
We have made four tissue specific ATP2B1 KO mice and overexpression ATP2B1 mice for these 3 years.Then, we reported the paper "Impaired nitric oxide production and increased blood pressure in systemic heterozygous ATP2B1 null mice."(J Hypertens. 2014 Jul;32(7):1415-23).
LPIN1 gene is a key regulator of circadian rhythm for blood pressure control. Now, we are making preparation for submitting these data as the first report of key regulator of circadian rhythm for blood pressure control.
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