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Establishment of adaptive criteria and protocol for accelerator-based BNCT

Research Project

Project/Area Number 25293267
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypePartial Multi-year Fund
Section一般
Research Field Radiation science
Research InstitutionKawasaki Medical School

Principal Investigator

Hiratsuka Junichi  川崎医科大学, 医学部, 教授 (30192298)

Co-Investigator(Kenkyū-buntansha) 神谷 伸彦  川崎医科大学, 医学部, 助教 (10614282)
櫻井 良憲  京都大学, 原子炉実験所, 准教授 (20273534)
粟飯原 輝人  筑波大学, 医学医療系, 准教授 (30268619)
田中 了  川崎医科大学, 医学部, 講師 (70412187)
河田 裕二郎  川崎医科大学, 医学部, 助教 (00804345)
森田 倫正  川崎医科大学, 医学部, 講師 (40341119)
Co-Investigator(Renkei-kenkyūsha) Kurebayashi Junichi  川崎医科大学, 医学部, 教授 (10248255)
Makino Eiichi  川崎医科大学, 医学部, 講師 (90314674)
Project Period (FY) 2013-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥18,200,000 (Direct Cost: ¥14,000,000、Indirect Cost: ¥4,200,000)
Fiscal Year 2017: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2016: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2015: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2014: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2013: ¥7,020,000 (Direct Cost: ¥5,400,000、Indirect Cost: ¥1,620,000)
KeywordsBNCT / accelerator / protocol / ホウ素中性子捕捉療法 / 頭頚部腫瘍 / 皮膚腫瘍 / 治療プロトコル / 加速器 / 放射線 / 粒子線治療 / 中性子捕捉療法 / 放射線治療 / 臨床成績 / 再発頭頸部癌 / 悪性黒色腫 / 再発頭頚部癌 / 難治性頭頸部癌
Outline of Final Research Achievements

This study has been carried out to estimate whether the reactor-based criteria is adaptable for the accelerator-based BNCT. 22 patients, 18 with the head and neck tumors and four with skin malignancies, received BNCT. Acceptable criteria are followings: (1) surgical treatment is rejected and not indicated, (2) the tumor depth is less than 6cm, and without distant metastases, (3) T/N ratio is more than 2.5 using 18F-BPA-PET. Patients with mass or nodular lesion received BPA-PET examination to estimate boron Tumor/Blood ratio. Our results are preliminary, as the patient cohort was very small. Furthermore, we calculated the irradiation doses on data obtained from previous studies. In the other words, we did not directly measure the boron concentration in each tumor. Nevertheless, our clinical responses after BNCT indicate that our calculations were accurate. This outcome strongly supports that it is possible to utilize the reactor-based criteria for the accelerator-based BNCT.

Report

(6 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Annual Research Report
  • 2015 Annual Research Report
  • 2014 Annual Research Report
  • 2013 Annual Research Report
  • Research Products

    (66 results)

All 2018 2017 2016 2015 2014 2013 Other

All Journal Article (24 results) (of which Int'l Joint Research: 5 results,  Peer Reviewed: 21 results,  Open Access: 11 results,  Acknowledgement Compliant: 1 results) Presentation (42 results) (of which Int'l Joint Research: 16 results,  Invited: 12 results)

  • [Journal Article] NOTE:Development of real-time epithermal neutron detector for boron neutron capture therapy.2017

    • Author(s)
      Tanaka H, Sakurai Y, Takata T, Watanabe T, Kawabata S, Suzuki M, Masunaga S, Taki K, Akabori K, Watanabe K, Ono K.
    • Journal Title

      Review of Scientific Instruments

      Volume: 88 Issue: 5 Pages: 56101-56101

    • DOI

      10.1063/1.4982036

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Selective boron delivery by intra-arterial injection of BSHWOW emulsion in hepatic cancer model for neutron capture therapy2017

    • Author(s)
      Yanagie H, Dewi N, Higashi S, Ikushima I, Seguchi K, Mizumachi R, Murata Y, Morishita Y, Shinohara A, Mikado S, Yasuda N, Fujihara M, Sakurai Y, Mouri K, Yanagawa M, Iizuka T, Suzuki M, Sakurai Y, Masunaga S, Ono K, et al.
    • Journal Title

      Br J Radiol

      Volume: 90 Issue: 1074 Pages: 20170004-20170004

    • DOI

      10.1259/bjr.20170004

    • URL

      https://pure.teikyo.jp/en/publications/6a3af490-b3af-43f8-944f-eca7e82f394f

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Block copolymer-boron cluster conjugate for effective boron neutron capture therapy of solid tumors.2017

    • Author(s)
      P. Mi, H. Yanagie, N. Dewi, H.-C. Yen, X. Liu, M. Suzuki, Y. Sakurai, K. Ono, H. Takahashi, H. Cabral, K. Kataoka,
    • Journal Title

      J. Control. Release

      Volume: 254 Pages: 1-9

    • DOI

      10.1016/j.jconrel.2017.03.036

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Application of Gel Detector in Boron Neutron Capture Therapy2017

    • Author(s)
      櫻井 良憲,内田 良平
    • Journal Title

      Japanese Journal of Medical Physics (Igakubutsuri)

      Volume: 37 Issue: 3 Pages: 190-194

    • DOI

      10.11323/jjmp.37.3_190

    • NAID

      130006337872

    • ISSN
      1345-5354, 2186-9634
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] イメージングプレートを用いた中性子捕捉療法ビーム成分分布の品質保証2017

    • Author(s)
      田中 憲一,櫻井 良憲,梶本 剛,田中 浩基,高田 卓志,村田 勲,玉置 真悟,遠藤 暁
    • Journal Title

      放射線

      Volume: 43 Pages: 3-7

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] BNCT for Head and Neck Cancer—History at Our Institution—2017

    • Author(s)
      粟飯原 輝人, 平塚 純一, 森田 倫正, 神谷 伸彦, 鈴木 実, 小野 公二, 熊田 博明, 原田 保
    • Journal Title

      Practica oto-rhino-laryngologica. Suppl.

      Volume: 149 Issue: 0 Pages: 227-240

    • DOI

      10.5631/jibirinsuppl.149.227

    • NAID

      130005529834

    • ISSN
      0912-1870, 2185-1557
    • Related Report
      2017 Annual Research Report
  • [Journal Article] 中性子捕捉療法2017

    • Author(s)
      平塚純一
    • Journal Title

      臨床腫瘍プラクティス

      Volume: 13 Pages: 67-70

    • Related Report
      2016 Annual Research Report
  • [Journal Article] Early clinical experience utilizing scintillator with optical fiber (SOF) detector in clinical boron neutron capture therapy: its issues and solutions2016

    • Author(s)
      M. Ishikawa, T. Yamamoto, A. Matsumura, J. Hiratsuka, S. Miyatake, I. Kato, Y. Sakurai, H. Kumada, S.J.Shrestha, K.Ono
    • Journal Title

      Radiation Oncology

      Volume: 11 (105) Issue: 1 Pages: 1-10

    • DOI

      10.1186/s13014-016-0680-0

    • NAID

      120007129420

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Evaluation of fluoride-18-labeled boronophenylalanine-positron emission tomography imaging for the assessment of boron neutron capture therapy in patients with recurrent head and neck squamous cell carcinoma2016

    • Author(s)
      T.Aihara, J.Hiratsuka, N.Fukumitsu, H.Ishikawa, N.Morita, H.Kumada, N.Kamitani, K.Ohnishi, M.Suzuki, H.Sakurai, T.Harada
    • Journal Title

      Otolaryngology

      Volume: 6 (6) Issue: 06 Pages: 1-5

    • DOI

      10.4172/2161-119x.1000277

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] In vivo evaluation of neutron capture therapy effectivity using calcium phosphate-based nanoparticles as Gd-DTPA delivery agent2016

    • Author(s)
      Novriana Dewi, Peng Mi, Hironobu Yanagie, Yuriko Sakurai, Yasuyuki Morishita, Masashi Yanagawa, Takayuki Nakagawa, Atsuko Shinohara, Takehisa Matsukawa, Kazuhito Yokoyama, Horacio Cabral, Minoru Suzuki, Yoshinori Sakurai, Hiroki Tanaka, Koji Ono, Nobuhiro Nishiyama, Kazunori Kataoka, Hiroyuki Takahashi
    • Journal Title

      Journal of Cancer Research and Clinical Oncology

      Volume: 142 Issue: 4 Pages: 767-775

    • DOI

      10.1007/s00432-015-2085-0

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Design study of multi-imaging plate system for BNCT irradiation field at Kyoto university reactor2016

    • Author(s)
      K.Tanaka, Y.Sakurai, T.Kajimoto, H.Tanaka, T.Takata and S.Endo
    • Journal Title

      Appl. Radiat. Isot.

      Volume: 115 Pages: 212-220

    • DOI

      10.1016/j.apradiso.2016.06.001

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Fatal carotid blowout syndrome after BNCT for head and neck cancers.2015

    • Author(s)
      Aihara T, Hiratsuka J, Ishikawa H, Kumada H, Ohnishi K, Kamitani N, Suzuki M, Sakurai H, Harada T.
    • Journal Title

      Applied Radiation and Isotopes

      Volume: 106 Pages: 202-206

    • DOI

      10.1016/j.apradiso.2015.08.007

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] ホウ素中性子捕捉療法2015

    • Author(s)
      平塚純一
    • Journal Title

      日本医師会雑誌

      Volume: 144 Pages: 262-262

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Advances in boron neutron capture therapy (BNCT) at kyoto university - From reactor-based BNCT to accelerator-based BNCT.2015

    • Author(s)
      Sakurai Y, Tanaka H, Takata T, Fujimoto N, Suzuki M, Masunaga S, Kinashi Y, Kondo N, Narabayashi M, Nakagawa Y, Watanabe T, Ono K, Maruhashi A.
    • Journal Title

      Journal- Korean Physical Society

      Volume: 67 Issue: 1 Pages: 76-81

    • DOI

      10.3938/jkps.67.76

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] The improvement of the energy resolution in epi-thermal neutron region of Bonner sphere using boric acid water solution moderator2015

    • Author(s)
      H.Ueda, H.Tanaka and Y.Sakurai
    • Journal Title

      Applied Radiation and Isotopes

      Volume: 104 Pages: 25-28

    • DOI

      10.1016/j.apradiso.2015.06.020

    • NAID

      120005672617

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Localized dose delivering by ion beam irradiation for experimental trial of establishing brain necrosis model2015

    • Author(s)
      T.Takata, N.Kondo, Y.Sakurai, H.Tanaka, T.Hasegawa, K.Kume and M.Suzuki
    • Journal Title

      Applied Radiation and Isotopes

      Volume: 105 Pages: 32-34

    • DOI

      10.1016/j.apradiso.2015.07.023

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Development of a dual phantom technique for measuring the fast neutron component of dose in boron neutron capture therapy.2015

    • Author(s)
      Sakurai Y, Tanaka H, Kondo N, Kinashi Y, Suzuki M, Masunaga S, Ono K, Maruhashi A.
    • Journal Title

      Medical Physics

      Volume: 42 Issue: 11 Pages: 6651-6657

    • DOI

      10.1118/1.4934243

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Improvement of depth dose distribution using multiple-field irradiation in boron neutron capture therapy2015

    • Author(s)
      N. Fujimoto, H. Tanaka, Y. Sakurai, T. Takata, N. Kondo, M. Narabayashi, Y. Nakagawa, T. Watanabe, Y. Kinashi, S. Masunaga, A. Maruhashi, K. Ono, M. Suzuki,
    • Journal Title

      Applied Radiation and Isotopes

      Volume: 106 Pages: 134-138

    • DOI

      10.1016/j.apradiso.2015.07.041

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Cutaneous Melanoma2015

    • Author(s)
      平塚純一、神谷伸彦、笹岡俊輔、桑原千晶
    • Journal Title

      RADIOISOTOPES

      Volume: 64 Issue: 1 Pages: 115-121

    • DOI

      10.3769/radioisotopes.64.115

    • NAID

      130004803061

    • ISSN
      0033-8303, 1884-4111
    • Related Report
      2014 Annual Research Report
  • [Journal Article] BNCT for advanced or recurrent head and neck cancer2014

    • Author(s)
      Aihara Teruhito, Morita Norimasa, Kamitani Nobuhiko, Kumada Hiroaki, Ono Koji, Hiratsuka Junichi, Harada Tamotsu.
    • Journal Title

      Applied Radiation and Isotopes

      Volume: 88 Pages: 12-15

    • DOI

      10.1016/j.apradiso.2014.04.007

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Boron neutron capture therapy outcomes for advanced or recurrent head and neck cancer2014

    • Author(s)
      Suzuki M, Kato I, Aihara T, Hiratsuka J, Yoshimura K, Niimi M, Kimura Y, Ariyoshi Y, Haginomori S, Sakurai Y, Kinashi Y, Masunaga S, et al, 計15名
    • Journal Title

      J Radiat Res

      Volume: 55(1) Issue: 1 Pages: 146-153

    • DOI

      10.1093/jrr/rrt098

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Boron neutron capture therapy for advanced salivary gland carcinoma in head and neck2013

    • Author(s)
      Teruhito Aihara, Norimasa Morita, Nobuhiko Kamitani, Hiroaki Kumada, Koji Ono, Junichi Hiratsuka, Tamotu Harada.
    • Journal Title

      Int J Clin Oncol

      Volume: 25 Issue: 3 Pages: 1-8

    • DOI

      10.1007/s10147-013-0580-3

    • Related Report
      2014 Annual Research Report 2013 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Effect of asbestos exposure on differentiation of cytotoxic T lymphocytes in MLR of human PBMCs2013

    • Author(s)
      Kumagai-takei N, Nishimura Y, Maeda M, Hayashi H, Matsuzaki H, Lee S, Hiratsuka J, Otsuki T
    • Journal Title

      Am J Respir Cell Mol Biol

      Volume: 49(1) Issue: 1 Pages: 28-36

    • DOI

      10.1165/rcmb.2012-0134oc

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Alteration of cytoskeletal molecules in a human T cell line caused by continuous exposure to chrysotile asbestos.2013

    • Author(s)
      Maeda, M., Chen, Y., Kumagai-Takei, N., Hayashi, H., Matsuzaki, H., Lee, S., Hiratsuka, JI., Nishimura, Y., Kimura, Y., Otsuki T.
    • Journal Title

      Immunobiology

      Volume: (in press) Issue: 9 Pages: 1184-91

    • DOI

      10.1016/j.imbio.2013.04.007

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Presentation] BNCT for vulvar melanoma and extramammary Paget's disease of the genital regions.2018

    • Author(s)
      Hiratsuka Junichi, Kamitani Nobuhiko, Tanaka Ryo, Suzuki Minoru, Ono Koji
    • Organizer
      The agenda of the 3rd annual academic conference of TSNCT, jointly with the 10th trilateral BNCT meeting between Taiwan and Japan
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Fundamental knowledge for microdosimetry in boron neutron capture therapy.2018

    • Author(s)
      Y. Sakurai
    • Organizer
      Micro-Mini & Nano Dosimetry Workshop and Innovative Technologies in Radiation Oncology (MMND-ITRO 2018)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Clinical Trial of BNCT in Japan-Contribution of BPA.2017

    • Author(s)
      Hiratsuka Junichi
    • Organizer
      16th International Meeting on Boron Chemistry (IMEBORON XVI)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Experience of preclinical and Clinical Trial of BNCT in Japan.2017

    • Author(s)
      Hiratsuka Junichi
    • Organizer
      3rd INTERNATIONAL SYMPOSIUM
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Clinical Trials of BNCT for melanoma and H&N tumor in Japan-Contribution of BPA-2017

    • Author(s)
      Hiratsuka Junichi
    • Organizer
      Symposium -Curreut Clinical Status of Boron Neutron Capture Therapy and Paths to the Future-
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Remote-Changeable Bonner-Sphere Spectrometer for Characterization of BNCT Irradiation Field.2017

    • Author(s)
      Y. Sakurai, H. Ueda, R. Uchida, T. Takata and H. Tanaka
    • Organizer
      The 13th Neutron and Ion Dosimetry Symposium (NEUDOS-13)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Current Status of BNCT based on Research Reactor R&D in Japan.2017

    • Author(s)
      Y. Sakurai, H. Tanaka, T. Takata, T. Watanabe, N. Kondo, Y. Kinashi, S. Masunaga, M. Suzuki, K. Ono and A. Maruhashi
    • Organizer
      The 3rd International Symposium on the Application of Nuclear Technology as a Key Element to Promote Competitive National Industrial Products: Energy, Health, Agriculture, Industry and Environment.
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Development of the pharmacokinetic-evaluation system for boron delivery agent using prompt gamma-ray analysis.2017

    • Author(s)
      Y. Sakurai, H. Michiue, M. Kitamatsu, T. Takata, H. Tanaka, N. Kondo and M. Suzuki
    • Organizer
      The 8th Japan-Korean Joint Meeting on Medical Physics
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] The present status of Boron Neutron Capture Therapy in Japan.2017

    • Author(s)
      Y. Sakurai
    • Organizer
      17th Asia-Oceania Congress of Medical Physics & 38th Annual Conference of Association of Medical Physicists of India (AOCMP- AMPICON 2017)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Present status and future plan for physical engineering and medical physics for BNCT in KURRI.2017

    • Author(s)
      Y. Sakurai, H. Tanaka, T. Takata, M. Suzuki, S. Masunaga, Y. Kinashi, N. Kondo, T. Watanabe, Y. Tamari, Y. Sanada, K. Ono and A. Maruhashi
    • Organizer
      9th Young Researchers’ Boron Neutron Capture Therapy Meeting
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 頭頸部癌に対するホウ素中性子捕捉療法 -当施設での歩み-2017

    • Author(s)
      粟飯原 輝人,平塚 純一,石川 仁,神谷 伸彦,福光 延吉,鈴木 実,小野 公二,熊田 博明,櫻井 英幸,原田 保
    • Organizer
      第41回日本頭頸部癌学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 再々発頭頸部扁平上皮癌における硼素中性子捕捉療法の治療効果予測因子の検討2017

    • Author(s)
      粟飯原 輝人,平塚 純一,石川 仁,大西 かよ子,福光 延吉, 神谷 伸彦, 原田 保, 櫻井 英幸
    • Organizer
      第54回日本癌治療学会学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Overview of the BNCT clinical studies at the university of tsukuba.2017

    • Author(s)
      Aihara T, Ishikawa H, Kumada H, Fukumitsu N, Ohnishi K, Nakai K, Yamamoto T, Matsumura A, Sakurai H.
    • Organizer
      9th Young Researchers BNCT Meeting.
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 頭頸部BNCTにおけるボーラスを用いた線量分布改善手法に関する一検討2016

    • Author(s)
      櫻井 良憲,田中 浩基,高田 卓志,近藤 夏子,渡邉 翼,木梨 友子,増永 慎一郎,鈴木 実,小野 公二,丸橋 晃
    • Organizer
      日本放射線腫瘍学会 第29回学術大会
    • Place of Presentation
      京都国際会館(京都市左京区)
    • Year and Date
      2016-11-25
    • Related Report
      2016 Annual Research Report
  • [Presentation] Recent research activities on boron neutron capture therapy in Kyoto University Research Reactor Institute2016

    • Author(s)
      Y.Sakurai, H.Tanaka, T.Takata, N.Kondo and M.Suzuki
    • Organizer
      2016 Korea Bioplus Incheon Global Conference
    • Place of Presentation
      Songdo Convensia (仁川, 韓国)
    • Year and Date
      2016-11-22
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Development of remote-changeable Bonner-sphere spectrometer for QA/QC in BNCT2016

    • Author(s)
      Y.Sakurai, H.Ueda, R.Uchida, T.Takata and H.Tanaka
    • Organizer
      17th International Congress on Neutron Capture Therapy
    • Place of Presentation
      University of Missouri (Columbia, USA)
    • Year and Date
      2016-10-06
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 放射線治療の新展開2016

    • Author(s)
      平塚 純一
    • Organizer
      第52回日本医学放射線学会秋季臨床大会
    • Place of Presentation
      京王プラザホテル(東京都新宿区)
    • Year and Date
      2016-09-17
    • Related Report
      2016 Annual Research Report
  • [Presentation] Progress in Reactor and Accelerator Based BNCT at Kyoto University Research Reactor Institute2016

    • Author(s)
      Y.Sakurai, H.Tanaka, T.Takata, N.Kondo, Y.Kinashi, S.Masunaga, M.Suzuki, K.Ono and A.Maruhashi
    • Organizer
      The 26th International Nuclear Physics Conference (INPC2016)
    • Place of Presentation
      Adelaide Convention Centre (Adelaide, Australia)
    • Year and Date
      2016-09-15
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 放射線による着色を利用した硼素中性子捕捉療法用照射場のビームプロファイル測定手法に関する検討2016

    • Author(s)
      櫻井 良憲,内田 良平,高田 卓志,田中 浩基
    • Organizer
      第112回日本医学物理学会学術大会
    • Place of Presentation
      沖縄コンベンションセンター(沖縄県宜野湾市)
    • Year and Date
      2016-09-09
    • Related Report
      2016 Annual Research Report
  • [Presentation] 日本におけるホウ素中性子捕捉療法(BNCT)の臨床研究について2016

    • Author(s)
      平塚 純一
    • Organizer
      第13回日本中性子捕捉療法学会学術大会
    • Place of Presentation
      東京大学伊藤国際学術研究センター 伊藤謝恩ホール(東京都文京区)
    • Year and Date
      2016-08-07
    • Related Report
      2016 Annual Research Report
  • [Presentation] BNCTにおけるQA/QCのための遠隔可変型ボナー球スペクトロメータの開発2016

    • Author(s)
      櫻井 良憲,上田 治明,内田 良平,高田 卓志,田中 浩基
    • Organizer
      第13回日本中性子捕捉療法学会学術大会
    • Place of Presentation
      東京大学伊藤国際学術研究センター 伊藤謝恩ホール(東京都文京区)
    • Year and Date
      2016-08-06
    • Related Report
      2016 Annual Research Report
  • [Presentation] 難治性頭頚部腫瘍に対する中性子捕捉療法の現状2016

    • Author(s)
      平塚 純一
    • Organizer
      第45回放射線による制癌シンポジウム
    • Place of Presentation
      I-site なんば(大阪府大阪市)
    • Year and Date
      2016-07-15
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] 硼素中性子捕捉療法における物理工学-基礎研究と治療現場との架け橋を意識して2016

    • Author(s)
      櫻井 良憲,田中 浩基,高田 卓志
    • Organizer
      第45回放射線による制癌シンポジウム
    • Place of Presentation
      I-site なんば(大阪府大阪市)
    • Year and Date
      2016-07-15
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] 究極の癌放射線治療を目指して-ホウ素中性子捕捉療法の展望-2016

    • Author(s)
      平塚 純一
    • Organizer
      21世紀播磨科学技術フォ-ラム 第50回セミナ-
    • Place of Presentation
      姫路商工会議所(兵庫県姫路市)
    • Year and Date
      2016-01-26
    • Related Report
      2015 Annual Research Report
  • [Presentation] Experience of preclinical trial of melanoma and head/neck cancer BNCT in Japan2015

    • Author(s)
      Hiratsuka Junichi
    • Organizer
      The 1st Academic Meeting of Taiwan Society of Neutron capture Therapy
    • Place of Presentation
      The Great Roots Forestry Spa Resort (New Taipei City, Taiwan)
    • Year and Date
      2015-12-05
    • Related Report
      2015 Annual Research Report
  • [Presentation] Clinical trials of Boron Neutron Capture Therapy for Head and Neck melanoma2015

    • Author(s)
      平塚 純一
    • Organizer
      日本放射線腫瘍学会 第28回学術大会
    • Place of Presentation
      ベイシア文化ホール・前橋商工会議所会館(群馬県前橋市)
    • Year and Date
      2015-11-19
    • Related Report
      2015 Annual Research Report
  • [Presentation] 頭頸・口腔 頭頸部がんに対する新規治療開発 筑波大学における頭頸部BNCT臨床研究経過報告2015

    • Author(s)
      粟飯原 輝人, 石川 仁, 和田 哲郎, 福光 延吉, 大西 かよ子, 中井 啓, 長谷川 正午, 硲田 猛真, 鈴木 実, 原 晃, 櫻井 英幸
    • Organizer
      第53回日本癌治療学会学術集会
    • Place of Presentation
      国立京都国際会館・グランドプリンスホテル京都(京都府京都市)
    • Year and Date
      2015-10-29
    • Related Report
      2015 Annual Research Report
  • [Presentation] Experience of preclinical and clinical trial of BNCT in Japan2015

    • Author(s)
      Hiratsuka Junichi
    • Organizer
      International Symposium―The application of nuclear technology to support national sustainable development
    • Place of Presentation
      The Auditorium,Satya Wacana Christian University(Indonesia)
    • Year and Date
      2015-10-27
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 頭頚部腫瘍に対するホウ素中性子捕捉療法の治療効果に及ぼす因子について2015

    • Author(s)
      神谷 伸彦, 森田 倫正, 粟飯原 輝人, 小野 公二, 平塚 純一
    • Organizer
      第12回日本中性子捕捉療法学会学術大会
    • Place of Presentation
      神戸学院大学 ポートアイランドキャンパス(兵庫県神戸市)
    • Year and Date
      2015-09-04
    • Related Report
      2015 Annual Research Report
  • [Presentation] 筑波大学における頭頸部BNCT臨床研究経過報告2015

    • Author(s)
      粟飯原 輝人, 石川 仁, 和田 哲郎, 福光 延吉, 大西 かよ子, 中井 啓, 長谷川 正午, 硲田 猛真, 中山 雅博, 田渕 経司, 奥村 敏之, 鈴木 実, 原 晃, 櫻井 英幸
    • Organizer
      第39回日本頭頸部癌学会
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Year and Date
      2015-06-03
    • Related Report
      2015 Annual Research Report
  • [Presentation] The principle and History of Neutron Capture Therapy2015

    • Author(s)
      Hiratsuka Junichi
    • Organizer
      15th International Congress of Radiation Reseach
    • Place of Presentation
      国立京都国際会館(京都府京都市)
    • Year and Date
      2015-05-25
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 頭頸部 悪性黒色腫に対する中性子捕捉療法の治療効果2014

    • Author(s)
      平塚純一, 神谷伸彦,森田倫正, 粟飯原輝人
    • Organizer
      日本放射線腫瘍学会第27回学術大会
    • Place of Presentation
      パシフィコ横浜会議センター(横浜)
    • Year and Date
      2014-12-11 – 2014-12-13
    • Related Report
      2014 Annual Research Report
  • [Presentation] 癌の新たな治療法と核医学 ホウ素中性子捕捉療法とPET検査2014

    • Author(s)
      平塚 純一
    • Organizer
      第54回日本核医学会学術総会
    • Place of Presentation
      大阪国際会議場.(大阪)
    • Year and Date
      2014-11-06 – 2014-11-08
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 皮膚悪性黒色腫BNCTの治療成績2014

    • Author(s)
      平塚純一, 神谷伸彦, 笹岡俊輔, 櫻井良憲, 鈴木実
    • Organizer
      第11回日本中性子捕捉療法学会学術大会
    • Place of Presentation
      大阪大学コンベンションセンター(吹田市)
    • Year and Date
      2014-07-05 – 2014-07-06
    • Related Report
      2014 Annual Research Report
  • [Presentation] 乳房外Paget病に対するBNCTの経験2014

    • Author(s)
      神谷伸彦, 平塚純一
    • Organizer
      第11回日本中性子捕捉療法学会学術大会
    • Place of Presentation
      大阪大学コンベンションセンター(吹田市)
    • Year and Date
      2014-07-05 – 2014-07-06
    • Related Report
      2014 Annual Research Report
  • [Presentation] 頸部癌治療と頸動脈破裂症候群.-BNCTを安全に行うために-2014

    • Author(s)
      粟飯原輝人, 森田倫正, 神谷伸彦, 熊田博明, 大西かよ子, 石川仁, 福光延吉, 鈴木実, 原田保, 櫻井良憲, 平塚純一
    • Organizer
      第11回日本中性子捕捉療法学会学術大会
    • Place of Presentation
      大阪大学コンベンションセンター(吹田市)
    • Year and Date
      2014-07-05 – 2014-07-06
    • Related Report
      2014 Annual Research Report
  • [Presentation] Clinical results of BNCT for Head and Neck melanoma2014

    • Author(s)
      Hiratsuka Junichi
    • Organizer
      16th International Congress on Neutron Capture Therapy
    • Place of Presentation
      Pörssitalo (the former venue of the Finnish Stock Exchange)(Helsinki,Finland)
    • Year and Date
      2014-06-14 – 2014-06-19
    • Related Report
      2014 Annual Research Report
  • [Presentation] A Study of Effective Dose for Tumor in BNCT2014

    • Author(s)
      Y. Sakurai, H. Tanaka, N. Fujimoto, N. Kondo, M. Narabayashi, Y.Nakagawa, T.Watanabe, Y. Kinashi, M. Suzuki, S. Masunaga, A. Maruhashi and K. Ono
    • Organizer
      16th International Congress on Neutron Capture Therapy
    • Place of Presentation
      Pörssitalo (the former venue of the Finnish Stock Exchange)(Helsinki,Finland)
    • Year and Date
      2014-06-14 – 2014-06-19
    • Related Report
      2014 Annual Research Report
  • [Presentation] 頭頸部進行癌における初期治療としての硼素中性子捕捉療法2013

    • Author(s)
      粟飯原 輝人, 神谷 伸彦, 森田 倫正, 宇野 雅子, 平塚 純一, 原田 保
    • Organizer
      第37回日本頭頸部癌学会
    • Place of Presentation
      京王プラザホテル(東京新宿)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 無色素性悪性黒色腫頸部リンパ節転移に対するBNCTの2年経過報告

    • Author(s)
      神谷 伸彦, 森田 倫正、粟飯原 輝人、櫻井 良憲、鈴木 実、小野 公二、平塚 純一
    • Organizer
      第10回日本中性子捕捉療法学会学術大会
    • Place of Presentation
      岡山大学(津島キャンパス)創立五十周年記念館(岡山)
    • Related Report
      2013 Annual Research Report
  • [Presentation] BNCTを施工したメラノーマの3例

    • Author(s)
      笹岡俊輔, 牧野栄一, 櫻井良憲, 丸橋晃, 小野公二, 藤本亘, 平塚純一
    • Organizer
      第10回日本中性子捕捉療法学会学術大会
    • Place of Presentation
      岡山大学(津島キャンパス)創立五十周年記念館(岡山)
    • Related Report
      2013 Annual Research Report
  • [Presentation] ホウ素中性子補足療法(BNCT)を施行した皮膚原発の悪性黒色腫10例(川崎医大症例)

    • Author(s)
      牧野英一, 笹岡俊輔, 桑原千晶, 牧野麻貴, 粟飯原輝人, 神谷伸彦, 平塚純一, 藤本亘
    • Organizer
      第260回日本皮膚科学会岡山地方会
    • Place of Presentation
      岡山コンベンションセンター 1Fイベントホール(岡山)
    • Related Report
      2013 Annual Research Report

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Published: 2013-05-21   Modified: 2019-07-29  

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