| Budget Amount *help |
¥17,940,000 (Direct Cost: ¥13,800,000、Indirect Cost: ¥4,140,000)
Fiscal Year 2015: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2014: ¥6,760,000 (Direct Cost: ¥5,200,000、Indirect Cost: ¥1,560,000)
Fiscal Year 2013: ¥6,630,000 (Direct Cost: ¥5,100,000、Indirect Cost: ¥1,530,000)
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| Outline of Final Research Achievements |
We aimed to induce organ regeneration of "iPanc" from "iGut" by using iPS cells. For clinical application, we tried to induce iPanc by using human iPS cells, but failed to induce human iPanc. We found that mouse iPS-derived heart (iHeart) and iGut have temperature-sensitive ability in motion, which were decreased under 35℃ and failed to move under 30℃. Now we are establishing iPS cells from mouse insulin promotor (MIP)-green fluorescence protein (GFP) mouse. Our results would provide useful information for organ regenerative medicine of iPanc from iGut.
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