Development of a catheter-based itravascular rotary blood pump for assisting selective blood circulation in heart failure
| Project/Area Number |
25293300
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Partial Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Cardiovascular surgery
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| Research Institution | National Cardiovascular Center Research Institute |
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Principal Investigator |
Sumikura Hirohito 国立研究開発法人国立循環器病研究センター, 研究所, 特任研究員 (20433998)
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| Co-Investigator(Kenkyū-buntansha) |
妙中 義之 国立研究開発法人国立循環器病研究センター, 研究開発基盤センター, 所長 (00142183)
巽 英介 国立研究開発法人国立循環器病研究センター, 研究所, 部長 (00216996)
大沼 健太郎 桐蔭横浜大学, 医用工学部, 講師 (50527992)
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| Co-Investigator(Renkei-kenkyūsha) |
TAKEWA Yoshiaki 国立研究開発法人国立循環器病研究センター, 研究所, 室長 (20332405)
TSUKIYA Tomonori 国立研究開発法人国立循環器病研究センター, 研究所, 室長 (00311449)
MIZUNO Toshihide 国立研究開発法人国立循環器病研究センター, 研究所, 室長 (40426515)
HOMMA Akihiko 東京電機大学, 理工学部, 教授 (20287428)
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| Project Period (FY) |
2013-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥18,070,000 (Direct Cost: ¥13,900,000、Indirect Cost: ¥4,170,000)
Fiscal Year 2015: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2014: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2013: ¥8,190,000 (Direct Cost: ¥6,300,000、Indirect Cost: ¥1,890,000)
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| Keywords | 補助循環装置 / 血液ポンプ / カテーテル / モータ / 心不全治療 |
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| Outline of Final Research Achievements |
In this study, a catheter-based intravascular rotary blood pump for assisting renal blood circulation was developed. The prototype blood pump was manufactured based on computational fluid dynamics analysis results and its pump performance was evaluated in in vitro experiment. In addition, the hydraulic performance of the prototype blood pump was evaluated using a mock circulation circuit which included renal arterial branch under pulsatile systemic hemodynamic condition. The results of in vitro experiments, a flow rate of 1 L/min for a 50 mmHg pressure head was achieved at rotational speed of approximately 25,000 rpm in the prototype blood pump. Additionally, the prototype blood pump was able to increase renal arterial flow and pressure of both renal arteries selectively. The developed catheter-based intravascular rotary blood pump displayed sufficient performance for assisting both renal arteries.
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Report
(5 results)
Research Products
(13 results)
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[Presentation] 選択的腎潅流用カテーテル式補助循環装置の改良と in vitro 評価2015
Author(s)
住倉博仁, 大沼健太郎, 花田繁, 築谷朋典, 水野敏秀, 本間章彦, 向林宏, 小嶋孝一, 武輪能明, 妙中義之, 巽英介
Organizer
日本定常流ポンプ研究会 2015
Place of Presentation
文京区
Year and Date
2015-11-19
Related Report
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[Presentation] 腎動脈補助用カテーテル式補助循環装置の開発と評価2015
Author(s)
住倉 博仁, 大沼健太郎, 花田 繁, 築谷朋典, 水野敏秀, 本間章彦, 向林 宏, 小嶋孝一, 武輪能明, 巽 英介
Organizer
第43回人工心臓と補助循環懇話会学術集会
Place of Presentation
静岡県熱海市
Year and Date
2015-02-20 – 2015-02-21
Related Report
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