Thermoregulation by stress hormones during perioperative period
| Project/Area Number |
25293328
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Partial Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Anesthesiology
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| Research Institution | Kagoshima University |
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Principal Investigator |
Kanmura Yuichi 鹿児島大学, 医歯学域医学系, 教授 (30211189)
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| Co-Investigator(Kenkyū-buntansha) |
KUWAKI Tomoyuki 鹿児島大学, 医歯学域医学系, 教授 (80205260)
HASEGAWA Maiko 鹿児島大学, 医歯学域医学系, 准教授 (20516637)
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| Research Collaborator |
KASHIWADANI Hideki
KUSUMOTO Ikue
KUROKI Chiharu
YAMAGUCHI Keiji
TASHIRO Shogo
YAMAGUCHI Ran
KAJIYA Katsuko
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥18,070,000 (Direct Cost: ¥13,900,000、Indirect Cost: ¥4,170,000)
Fiscal Year 2015: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2014: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2013: ¥8,580,000 (Direct Cost: ¥6,600,000、Indirect Cost: ¥1,980,000)
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| Keywords | 防御反応 / オレキシン / 周術期管理 / 遺伝子改変マウス / 体温調節 / ストレス / TRPA1 / 呼吸調節 / 循環調節 / シバリング / 低体温 / ストレスホルモン |
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| Outline of Final Research Achievements |
The aim of this study was to reveal possible modification by stress hormones of thermoregulation during perioperative period. From clinical and experimental studies, we found that orexin is critically important for thermoregulation during perioperative period. We conclude that we should pay special attention to keep body temperature of narcolepsy patients who lack orexin within a normal range to avoid aversive side effects from anesthesia.
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Report
(4 results)
Research Products
(27 results)
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[Presentation] 睡眠・覚醒に伴う呼吸調節の変化2014
Author(s)
桑木共之
Organizer
日本睡眠学会第39回定期学術集会
Place of Presentation
徳島県郷土文化会館（徳島市）
Year and Date
2014-07-03 – 2014-07-04
Related Report
Invited
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