| Budget Amount *help |
¥17,290,000 (Direct Cost: ¥13,300,000、Indirect Cost: ¥3,990,000)
Fiscal Year 2015: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2014: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2013: ¥10,270,000 (Direct Cost: ¥7,900,000、Indirect Cost: ¥2,370,000)
|
|---|
| Outline of Final Research Achievements |
Our investigation showed that the respiratory neuron groups including the ventral respiratory group and the retrotrapezoid/parafacial respiratory group in the medulla oblongata play a role in the regulation of the non-respiratory laryngeal movements such as vocalization, coughing, and swallowing. Furthermore, this study suggested that the kernel neural networks involving coughing or swallowing could be located within the medulla caudal to the retrotrapezoid/parafacial respiratory group.
We also clarified the role of steroid hormones in the functional expression of fibroblasts in the vocal folds regarding production of extracellular matrix.
In addition, the immunohistochemistry combined with injection of the retrograde tracer into the larynx demonstrated the specific features of immunopositive neurons for the sex steroid hormone receptor in the dorsal motor nucleus of the vagus.
|
