Euro-Japan collaborative field work for the understanding of symbiotic evolution of marine microbes
| Project/Area Number |
25303008
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (B)
|
| Allocation Type | Partial Multi-year Fund |
|---|
| Section | 海外学術 |
|---|
| Research Field |
Biomolecular chemistry
|
|---|
| Research Institution | Waseda University |
|---|
Principal Investigator |
Nakao Yoichi 早稲田大学, 理工学術院, 教授 (60282696)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
YAMASHITA Jun 京都大学, iPS細胞研究所, 教授 (50335288)
|
|---|
| Co-Investigator(Renkei-kenkyūsha) |
KIMURA Hiroshi 東京工業大学, 大学院生命理工学研究科, 教授 (30241392)
IKURA Tsuyoshi 京都大学, 放射線生物研究センター, 准教授 (70335686)
|
|---|
| Project Period (FY) |
2013-04-01 – 2016-03-31
|
| Project Status |
Completed (Fiscal Year 2015)
|
| Budget Amount *help |
¥14,300,000 (Direct Cost: ¥11,000,000、Indirect Cost: ¥3,300,000)
Fiscal Year 2015: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2014: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2013: ¥6,370,000 (Direct Cost: ¥4,900,000、Indirect Cost: ¥1,470,000)
|
|---|
| Keywords | 海洋天然物化学 / 共生微生物 / エピジェネティクス / 海綿 / 生理活性物質 / メタボローム解析 / メタゲノム解析 / 国際研究者交流 |
|---|
| Outline of Final Research Achievements |
We have compared the metabolome analysis of marine sponge by LC-MS/MS. As the results, we have found the difference between the matabolite profiles of two closely related sponge samples collected in Italy and Japan. Also, we could isolate highly novel microorganisms from the sponge of genus Theonella by means of newly developed Diffusion Chamber method. Through this project, a sound base for the collaborative activity between Italy-Japan marine natural products chemistry has been established.
|
Report
(4 results)
Research Products
(15 results)
-
-
[Journal Article] A genetically encoded FRET probe to detect intranucleosomal histone H3K9 or H3K14 acetylation using BRD4, a BET family member2016
Author(s)
Nakaoka, S., Sasaki, K., Ito, A., Nakao, Y., and Yoshida, M.
-
Journal Title
ACS Chem. Biol.
Volume: 11
Issue: 3
Pages: 729-733
DOI
Related Report
Peer Reviewed
-
-
-
[Journal Article] Insights on pregnane-X-receptor modulation. Natural and2014
Author(s)
Valentina Sepe, Claudio D’Amore, Raffella Ummarino, Barbara Renga, Maria Valeria D’Auria, Ettore Novellino, Annamaria Sinisi, Orazio Taglialatela-Scafati, Yoichi Nakao, Vittorio Limongelli, Angela Zampella, Stefano Fiorucci
-
Journal Title
Eur. J. Med. Chem.
Volume: 73
Pages: 126-134
Related Report
Peer Reviewed
-
-
-
-
-
-
-
-
-
-
