• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Fate of resistant bacteria in Asian river basin and multiple drug resistance of beta-lactamase production bacteria

Research Project

Project/Area Number 25303019
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypePartial Multi-year Fund
Section海外学術
Research Field Civil and environmental engineering
Research InstitutionKyoto University

Principal Investigator

Yamashita Naoyuki  京都大学, 工学(系)研究科(研究院), 講師 (90391614)

Co-Investigator(Kenkyū-buntansha) Tanaka Hiroaki  京都大学, 大学院工学研究科, 教授 (70344017)
Mizuno Tadao  京都大学, 大学院工学研究科, 講師 (00422981)
Ihara Masaru  京都大学, 大学院工学研究科, 研究員 (70450202)
Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥16,900,000 (Direct Cost: ¥13,000,000、Indirect Cost: ¥3,900,000)
Fiscal Year 2015: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2014: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2013: ¥7,540,000 (Direct Cost: ¥5,800,000、Indirect Cost: ¥1,740,000)
Keywords薬剤耐性菌 / 河川流域 / ラクタマーゼ / βラクタマーゼ / 多剤耐性菌
Outline of Final Research Achievements

Occurrence of resistant bacteria in Asian river basin such as Japan, China and Bangladesh was surveyed in this research. From the results in the Katsura river, Japan, ratio of resistant bacteria and values of Multi-Antibiotic Resistance (MAR) index for sewage effluents were higher than these for river water, which indicates that sewage effluents will be important sources of resistant bacteria in river basin. Similar results were obtained from the survey in China and Bangladesh river basin. On the MAR index obtained from Asian river basin, the values in Bangladesh were higher than these in Japan.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Annual Research Report
  • 2013 Annual Research Report
  • Research Products

    (28 results)

All 2016 2015 2014 2013 Other

All Int'l Joint Research (2 results) Journal Article (9 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 8 results,  Acknowledgement Compliant: 5 results,  Open Access: 3 results) Presentation (17 results) (of which Int'l Joint Research: 1 results)

  • [Int'l Joint Research] 清華大学(中国)

    • Related Report
      2015 Annual Research Report
  • [Int'l Joint Research] Jessore University(バングラデシュ)

    • Related Report
      2015 Annual Research Report
  • [Journal Article] Prediction, risk and control of anti-influenza drugs in the Yodo River Basin, Japan during seasonal and pandemic influenza using the transmission model for infectious disease2015

    • Author(s)
      Azuma, T., Nakada, N., Yamashita, N., Tanaka, H.
    • Journal Title

      Science of the Total Environment

      Volume: 521 Pages: 68-74

    • DOI

      10.1016/j.scitotenv.2015.03.069

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Detection of Peramivir and Laninamivir, New Anti-Influenza Drugs, in Sewage Effluent and River Waters in Japan2015

    • Author(s)
      Azuma T, Ishiuchi H, Inoyama T, Teranishi Y, Yamaoka M, Sato T, Yamashita Y, Tanaka H
    • Journal Title

      PLOS one

      Volume: 10(6) Issue: 6 Pages: e0131412-e0131412

    • DOI

      10.1371/journal.pone.0131412

    • NAID

      120005763392

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Evaluation of concentrations of pharmaceuticals detected in sewage influents in Japan by using annual shipping and sales data2015

    • Author(s)
      Azuma, T., Nakada, N., Yamashita, N., Tanaka, H.
    • Journal Title

      Chemosphere

      Volume: 138 Pages: 770-776

    • DOI

      10.1016/j.envint.2016.03.001

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Optimisation of the analysis of antiinfluenza drugs in wastewater and surface water2014

    • Author(s)
      Azuma, T., Nakada, N., Yamashita, N., Tanaka, H.
    • Journal Title

      International Journal of Environmental Analytical Chemistry

      Volume: 94(9) Issue: 9 Pages: 853-862

    • DOI

      10.1080/03067319.2014.921290

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Evaluation of the photolysis of pharmaceuticals within a river by 2 year field observations and toxicity changes by sunlight2014

    • Author(s)
      Seiya Hanamoto, Tsukasa Kawakami, Norihide Nakada, Naoyuki Yamashita and Hiroaki Tanaka
    • Journal Title

      Environmental Science: Processes & Impacts

      Volume: 16 Issue: 12 Pages: 2796-2803

    • DOI

      10.1039/c4em00448e

    • NAID

      120005657910

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Elevated risk from estrogens in the Yodo River basin (Japan) in winter and ozonation as a management option2014

    • Author(s)
      Kumar, V., Hanamoto, S., Johnson, A.C., Yamashita, N., Nakada, N., Tanaka, H.
    • Journal Title

      Environmental Science-Processes & Impacts

      Volume: 16(2) Issue: 2 Pages: 232-238

    • DOI

      10.1039/c3em00219e

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] 医薬品類による水環境汚染と薬剤耐性菌の発生2013

    • Author(s)
      田中宏明,山下尚之,堅川陽平
    • Journal Title

      化学療法の領域

      Volume: 29 (6) Pages: 92-96

    • Related Report
      2013 Annual Research Report
  • [Journal Article] Modeling the Photochemical Attenuation of Down-the-Drain Chemicals during River Transport by Stochastic Methods and Field Measurements of Pharmaceuticals and Personal Care Products2013

    • Author(s)
      Hanamoto, S., Nakada, N., Yamashit a, N., Tanaka, H.
    • Journal Title

      Environmental Science and Technology

      Volume: 47 Issue: 23 Pages: 13571-13577

    • DOI

      10.1021/es4035478

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Mass balance of anti-influenza drugs discharged into the Yodo River system, Japan, under an influenza outbreak2013

    • Author(s)
      Takashi Azuma, Norihide Nakada, Naoyuki Yamashita, Hiroaki Tanaka
    • Journal Title

      Chemosphere

      Volume: 93 Issue: 9 Pages: 1672-7

    • DOI

      10.1016/j.chemosphere.2013.05.025

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Presentation] 河川における医薬品類の底質への移行に関する検討2016

    • Author(s)
      花本征也、中田典秀、山下尚之、田中宏明
    • Organizer
      第50回日本水環境学会年会
    • Place of Presentation
      徳島
    • Year and Date
      2016-03-16
    • Related Report
      2015 Annual Research Report
  • [Presentation] "被災下水処理場の暫定処理水での塩素消毒と代替消毒技術による指標微生物の不活化 "2015

    • Author(s)
      朴耿洙、山下尚之、田中宏明
    • Organizer
      日本水環境学会 水中の健康関連微生物研究委員会シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2015-12-15
    • Related Report
      2015 Annual Research Report
  • [Presentation] 河川水に含まれる医薬品生理活性の測定2015

    • Author(s)
      井原賢、花本征也、Zhang Han、田中宏明
    • Organizer
      第18回環境ホルモン学会
    • Place of Presentation
      栃木
    • Year and Date
      2015-12-10
    • Related Report
      2015 Annual Research Report
  • [Presentation] 河川水からの医薬品生理活性の検出2015

    • Author(s)
      井原賢、花本征也、Han Zhang、田中宏明
    • Organizer
      第21回日本環境毒性学会
    • Place of Presentation
      東京
    • Year and Date
      2015-08-01
    • Related Report
      2015 Annual Research Report
  • [Presentation] 下水処理場内の緑膿菌の薬剤耐性と水環境における大腸菌との関係性2015

    • Author(s)
      郁承冕、山下尚之、田中宏明
    • Organizer
      第37回京都大学環境衛生工学研究会シンポジウム
    • Place of Presentation
      京都
    • Year and Date
      2015-07-31
    • Related Report
      2015 Annual Research Report
  • [Presentation] Detection of physiological activities of pharmaceuticals in river water in Japan2015

    • Author(s)
      Masaru Ihara, Han Zhang, Seiya Hanamoto, and Hiroaki Tanaka
    • Organizer
      SETAC Europe 25th Annual Meeting
    • Place of Presentation
      Barcelona, Spain
    • Year and Date
      2015-05-07
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 河川における医薬品類の底質への収着に関する検討2015

    • Author(s)
      花本征也,中田典秀,山下尚之,田中宏明
    • Organizer
      第49回日本水環境学会年会
    • Place of Presentation
      金沢大学,金沢市
    • Year and Date
      2015-03-16 – 2015-03-18
    • Related Report
      2014 Annual Research Report
  • [Presentation] Sorption of pharmaceuticals from river water onto sediment: harnessing river as treatment system in water reuse2014

    • Author(s)
      Seiya Hanamoto, Norihide Nakada, Naoyuki Yamashita, Hiroaki Tanaka
    • Organizer
      2nd International Symposium on Development and Evaluation of Water Reuse Technologies for the Establishment of 21st Century Type Water Cycle System
    • Place of Presentation
      Danang, Vietnam
    • Year and Date
      2014-11-14
    • Related Report
      2014 Annual Research Report
  • [Presentation] The Fate of selected Pharmaceuticals in a section of the River Thames and in Sewage Treatment Plants2014

    • Author(s)
      S. Hanamoto, N. Nakada, M.D. Jürgens, A. C. Johnson, N. Yamashita, H. Tanaka
    • Organizer
      IWA World Water Congress
    • Place of Presentation
      Lisbon, Portogal
    • Year and Date
      2014-09-21 – 2014-09-26
    • Related Report
      2014 Annual Research Report
  • [Presentation] 次世代シーケンサーを用いた、水環境における薬剤耐性遺伝子の大規模検出2014

    • Author(s)
      井原賢,堅川陽平,李善太,松田知成,山下尚之,田中宏明
    • Organizer
      第17回日本水環境学会シンポジウム講演集
    • Place of Presentation
      滋賀県立大学,彦根市
    • Year and Date
      2014-09-08 – 2014-09-10
    • Related Report
      2014 Annual Research Report
  • [Presentation] 河川流下過程における医薬品類の減衰:実態把握とメカニズム解明2014

    • Author(s)
      花本征也,中田典秀,山下尚之,田中宏明
    • Organizer
      第17回日本水環境学会シンポジウム講演集
    • Place of Presentation
      滋賀県立大学,彦根市
    • Year and Date
      2014-09-08 – 2014-09-10
    • Related Report
      2014 Annual Research Report
  • [Presentation] 下水処理過程における緑膿菌の動態とその薬剤耐性2014

    • Author(s)
      郁 承冕,山下尚之,堅川 陽平,田中 宏明
    • Organizer
      第36 回 京都大学環境衛生工学研究会シンポジウム
    • Place of Presentation
      京都大学,京都
    • Year and Date
      2014-07-31 – 2014-08-01
    • Related Report
      2014 Annual Research Report
  • [Presentation] 河川流下過程における医薬品類の光分解に関する研究

    • Author(s)
      花本征也,中田典秀,山下尚之,田中宏明
    • Organizer
      第35回京都大学環境衛生工学研究会シンポジウム
    • Place of Presentation
      京都
    • Related Report
      2013 Annual Research Report
  • [Presentation] Photolysis of PPCPs along the river stretch based on the stochastic model, laboratory experiment and the field survey

    • Author(s)
      Hanamoto, S., Nakada, N., Yamashita, N., Tanaka, H.
    • Organizer
      Micropol & Ecohazard 2013
    • Place of Presentation
      Zurich, Switzerland
    • Related Report
      2013 Annual Research Report
  • [Presentation] Analysis of microbial community of wastewater treatment plant by next generation sequencing

    • Author(s)
      Ihara M, Lee S, Katakawa Y, Yamashita N, Matsuda T, Tanaka H
    • Organizer
      WaterMicro 2013
    • Place of Presentation
      Florianopolis, Brazil
    • Related Report
      2013 Annual Research Report
  • [Presentation] 都市河川における医薬品類の雨天時存在実態の把握

    • Author(s)
      花本征也,中田典秀,山下尚之,田中宏明
    • Organizer
      第50回下水道研究発表会
    • Place of Presentation
      東京
    • Related Report
      2013 Annual Research Report
  • [Presentation] 淀川水系における抗がん剤成分の挙動把握

    • Author(s)
      東剛志,井ノ山智美,寺西裕亮,石打浩隆,山岡美里,三野芳紀,中田典秀,山下尚之,田中宏明
    • Organizer
      第35回京都大学環境衛生工学研究会シンポジウム
    • Place of Presentation
      京都
    • Related Report
      2013 Annual Research Report

URL: 

Published: 2013-05-21   Modified: 2022-02-01  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi