| Budget Amount *help |
¥17,940,000 (Direct Cost: ¥13,800,000、Indirect Cost: ¥4,140,000)
Fiscal Year 2017: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2016: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2015: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2014: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2013: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
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| Outline of Final Research Achievements |
①After 1960’, ALS/PDC, especially ALS, has been decreasing in the Kii peninsula subsequently to on Guam island.②No or only subtle accumulation of BMAA (β-Methylamino-L-alanine) in the brains of Kii patients.
③GWAS revealed candidate SNPs of 5 chromosomes in the patients with Kii ALS/PDC. The diagnostic criteria and severity index were published under supervision by the Japanese Society of Neurology.④New articles regarding neurotoxic BMAA, cerebellar neuropathology, OPTN neuropathology and nitration stress have been accepted by several international journals.
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