Comprehensive Assessment of Prevalence and Trends of Gestational Diabetes Mellitus among Bangladeshi Rural Women: A multidisciplinary investigation from basic epidemiology to genetic screening
Project/Area Number |
25305034
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Research Category |
Grant-in-Aid for Scientific Research (B)
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Allocation Type | Partial Multi-year Fund |
Section | 海外学術 |
Research Field |
Obstetrics and gynecology
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Research Institution | University of Tsukuba |
Principal Investigator |
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Co-Investigator(Kenkyū-buntansha) |
MIZUTANI Taro 筑波大学, 医学医療系, 教授 (80181890)
IWASHIMA Yoshio 国立研究開発法人国立循環器病センター, 高血圧・腎臓科, 医長 (80448068)
OKAZAKI Osamu 国立国際医療研究センター, 循環器内科, 医長 (30203970)
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Project Period (FY) |
2013-04-01 – 2016-03-31
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Project Status |
Completed (Fiscal Year 2015)
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Budget Amount *help |
¥18,330,000 (Direct Cost: ¥14,100,000、Indirect Cost: ¥4,230,000)
Fiscal Year 2015: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2014: ¥7,020,000 (Direct Cost: ¥5,400,000、Indirect Cost: ¥1,620,000)
Fiscal Year 2013: ¥8,710,000 (Direct Cost: ¥6,700,000、Indirect Cost: ¥2,010,000)
|
Keywords | 妊娠中糖尿病 / バングラデシュ / 疫学 / 遺伝学 |
Outline of Final Research Achievements |
Prevalence of gestational diabetes mellitus (GDM) in Bangladesh is 11.5% (urban) and 10.8% (rural) which increases with maternal age and number of parity. % of metabolic profile parameters among GDM cases in Bangladesh: high LDL-C (25.8%); low HDL-C (65.5%); hypertriglyceridemia (55.5%); hypercholesterolemia (26.4%); and metabolic syndrome (35.4%). 11.62% GDM cases have family history of DM. 90% rural pregnant women in Bangladesh do not know about GDM. Still in Bangladesh, in rural context, 50% pregnant women have no antenatal care. Top ranked risk factors for GDM: hypertension, metabolic syndrome, family history of hypertension, family history of diabetes, lack of regular exercise, lack of education, lack of health awareness and increased age in this population. The present study is the first report describing prevalence of GDM in Bangladesh and calls for urgent action to stop and prevent diabetes development in pregnancy and the associated complications both for mother and child.
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Report
(4 results)
Research Products
(60 results)
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[Journal Article] Assessment of Circulatory Levels of Endothelin-1 in Diabetic Subjects Screened Through a Cross Sectional Study from Rural Women in Bangladesh2015
Author(s)
M.A. Rahman, S. Jesmin, C.N. Mowa, F. Sohael, J. Kamiyama, A.K.M.A. Habib, N. Shimojo, M.M. Islam, M. Moroi, O. Okazaki, N. Yamaguchi, S. Kawano, T. Mizutani, Y. Iwashima
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Journal Title
International Journal of Diabetes and Clinical Research
Volume: 2
Pages: 1-5
Related Report
Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
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[Journal Article] Nationwide Non-Communicable Disease Risk Factors Profile in Bangladesh.2015
Author(s)
S. Jesmin, M.A. Rahman, A.K.M.A. Habib, M.M. Islam, S.N. Sultana, S. Zaedi, T. Khatun, F. Sohael, N. Yamaguchi, O. Okazaki, Y. Iwashima, S. Kawano.
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Journal Title
Journal of Hypertension
Volume: 33
Issue: Supplement 2
Pages: 2-2
DOI
Related Report
Peer Reviewed / Open Access / Int'l Joint Research
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[Journal Article] Assessment of Circulatory Endothelin-1 Level among Preand Post-Menopausal Rural Women in Bangladesh: Result from a Population-Based Study.2015
Author(s)
T. Khatun, S. Jesmin, N. Yamaguchi, J. Kamiyama, S. Akter, S.N. Sultana, M.M. Islam, O. Okazaki, S. Kawano, H. Akashi, T. Mizutani, T. Miyauchi, M.A. Rahman, A.K.M. A. Habib
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Journal Title
Annals of Vascular Medicine and Research
Volume: 2(2)
Related Report
Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
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[Journal Article] Higher circulatory level of endothelin-1 in hypertensive subjects screened through a cross-sectional study of rural Bangladeshi women.2015
Author(s)
Akter S, Jesmin S, Iwashima Y, Hideaki S, Rahman MA, Islam MM, Moroi M, Shimojo N, Yamaguchi N, Miyauchi T, Kawano S, Mizutani T, Kawano Y.
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Journal Title
Hypertens Res.
Volume: 38(3)
Issue: 3
Pages: 208-212
DOI
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
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[Journal Article] Assessment of Circulatory Endothelin-1 Level among Preand Post-Menopausal Rural Women in Bangladesh: Result from a Population-Based Study2015
Author(s)
Khatun T, Jesmin S, Yamaguchi N, Kamiyama J, Akter S, Sultana SN, Islam M, Okazaki O, Kawano S, Akashi H, Mizutani T, Miyauchi T, Rahman A, Habib AKMA
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Journal Title
Annals of Vascular Medicine & Research
Volume: 1
Pages: 1014-1014
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
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[Journal Article] Assessment of Circulatory Levels of Endothelin-1 in Diabetic Subjects Screened Through a Cross Sectional Study from Rural Women in Bangladesh2015
Author(s)
Rahman MA, Jesmin S, Mowa CN, Sohael F, Kamiyama J, Habib AKMA, Shimojo N, Islam MM, Moroi M, Okazaki O, Yamaguchi N, Kawano S, Mizutani T, Iwashima Y
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Journal Title
International Journal of Diabetes and Clinical Research
Volume: 2
Pages: 1-1
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
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[Journal Article] Effects of selective endothelin (ET)-A receptor antagonist versus dual ET-A/B receptor antagonist on hearts of streptozotocin-treated diabetic rats.2014
Author(s)
Miyauchi Y, Jesmin S, Sakai S, Kamiyama J, Shimojo N, Rahman A, Islam M, Zaedi S, Maeda S, Maruyama H, Mizutani T, Homma S, Aonuma K, Miyauchi T.
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Journal Title
Life Sciences
Volume: 111(1-2)
Issue: 1-2
Pages: 6-11
DOI
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
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[Journal Article] Endothelin-1 and Metabolic Syndrome in Bangladeshi Rural Women2014
Author(s)
Islam MM, Jesmin S, Akter S, Mowa CN, Sakuramoto H, Chowdhury SR, Rahman A, Habib AKMA, Okazaki O, Shimojo N, Miyauchi T, Kawano S, Mizutani T
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Journal Title
Annals of Vascular Medicine & Research
Volume: 1
Pages: 1008-1008
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
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[Journal Article] Screening for gestational diabetes mellitus in Bogra sadar, Bogra Bangladesh.2014
Author(s)
Jesmin S, Rahman A, Sohael F, Akter S, Islam MM, Khatun MT, Sultana SN, Mamun AA, Akashi H, Habib AKMA.
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Journal Title
Journal of Shaheed Ziaur Rahman Medical College
Volume: 20
Pages: 19-24
Related Report
Peer Reviewed / Acknowledgement Compliant
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[Presentation] An investigation on the nationwide prevalence and associated risk factors of anemia in reproductive ever married women in Bangladesh2014
Author(s)
Jesmin S, Rahman MA, Mamun AA, Islam MM, Sakuramoto Hideaki, Sabiruzzaman M, Khatun T, Alam ATMJ, Sultana SN, Sultana SN, Sohael F, Rahamn S
Organizer
Celebration of 2nd Public Health Foundation Day & Scientific Seminar
Place of Presentation
ダッカ、バングラデシュ
Year and Date
2014-12-07 – 2014-12-08
Related Report
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[Presentation] Higher level of endothelin-1 in hypertensive Rural Women in Bangladesh. Results of a Community based cross-sectional study2014
Author(s)
Rahman MA, Jesmin S, Iwashima Y, Ali A, Akter S, Khan A, Islam MM, Moroi M, Yamaguchi N, Shimojo N, Kawano S
Organizer
The 3rd International Congress on Lipid Metabolism & Atherosclerosis (ICLA 2014)
Place of Presentation
ソウル
Year and Date
2014-09-12 – 2014-09-13
Related Report
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[Presentation] An analysis of association between circulatory level of endothelin-1 and metabolic syndrome in Bangladeshi rural women2014
Author(s)
Rahman MA, Jesmin S, Islam MM, Habib AKMA, Akter S, Shimojo N, Sohael F, Zaedi S, Yamaguchi N, Moroi M, Okazaki O, Hiroe M, Kawano S
Organizer
The 3rd International Congress on Lipid Metabolism & Atherosclerosis (ICLA 2014)
Place of Presentation
ソウル
Year and Date
2014-09-12 – 2014-09-13
Related Report
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[Presentation] Metabolic syndrome among rural Bangladeshi women2014
Author(s)
Rahman MA, Jesmin S, Islam MM, Khatun T, Sultana SN, Yamaguchi N, Moroi M, Okazaki O, Hiroe M, Kawano S.
Organizer
The 3rd International Congress on Lipid Metabolism & Atherosclerosis (ICLA 2014)
Place of Presentation
ソウル
Year and Date
2014-09-12 – 2014-09-13
Related Report
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[Presentation] Potential association between circulatory level of endothelin-1 and metabolic syndrome in Bangladeshi rural women: a population-based cross-sectional study2013
Author(s)
Islam M, Jesmin S, Rahman A, Habib AKMA, Akter S, Shimojo N, Zaedi S, Yamaguchi N, Moroi M, Kimura S, Okazaki O, Hiroe M, Miyauchi T, Kawano S, Akashi H, Mizutani T
Organizer
The Thirteenth International Conference on Endothelin
Place of Presentation
東京
Related Report
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[Presentation] Higher circulatory level of endothelin-1 in hypertensive subjects screened through a cross sectional study in rural Bangladeshi women2013
Author(s)
Akter S, Jesmin S, Rahman A, Habib AKMA, Shimojo N, Islam M, Zaedi S, Yamaguchi N, Moroi M, Kimura S, Okazaki O, Miyauchi T, Kawano S, Akashi H, Mizutani T
Organizer
The Thirteenth International Conference on Endothelin
Place of Presentation
東京
Related Report
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[Presentation] Assessment of circulatory endothelin-1 level among pre- and post-menopausal rural women in Bangladesh: result from a population-based study2013
Author(s)
Khatutn T, Jesmin S, Rahman A, Habib AKMA, Shimojo N, Islam M, Zaedi S, Yamaguchi N, Moroi M, Kimura S, Okazaki O, Miyauchi T, Kawano S, Akashi H, Mizutani T
Organizer
The Thirteenth International Conference on Endothelin
Place of Presentation
東京
Related Report
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[Presentation] elective endothelin (ET)-A receptor antagonist and dual ET-A/B receptor antagonist are effective in preventing the decrease in VEGF signaling and inadequate coronary collateral development in the diabetic hearts2013
Author(s)
Miyauchi Y, Jesmin S, Shimojo N, Maeda S, Sakai S, Yokota T, Zaedi S, Mizutani T, Homma S, Aonuma K, Miyauchi T
Organizer
The Thirteenth International Conference on Endothelin
Place of Presentation
東京
Related Report
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[Presentation] Endothelin antagonism and diabetic erectile dysfunction: Changes in VEGF and NO in type I diabetic penis and effects of endothelin antagonism2013
Author(s)
Zaedi S, Jesmin S, Shimojo N, Sakai S, Maeda S, Miyauchi Y, Yokota T, Mizutani T, Homma S, Aonuma K, Miyauchi T
Organizer
The Thirteenth International Conference on Endothelin
Place of Presentation
東京
Related Report
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[Presentation] Disruption of components of vascular endothelial groth factor angiogenic signaling system in metabolic syndrome: Findings from a study conducted in rural Bangladeshi women2013
Author(s)
Jesmin S, Mamun AA, Akter S, Rahman MM, Islam MM, Khatun T, Rahman A, Sohael F, Sultana SN, Mizutani T
Organizer
World Diabetes Congress Melbourne 2013
Place of Presentation
Melbourne, Australia
Related Report
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[Presentation] Potential association between disrupted VEGF angiogenic signaling and metabolic syndrome in Bangladeshi rural women.
Author(s)
Jesmin S, Akter S, Shimojo N, Islam MM, Zaedi S, Yamaguchi N, Moroi M, Kimura S, Okazaki O, Hiroe M, Kawano S, Akashi H, Mizutani T
Organizer
2013 overseas scientific research Festa
Place of Presentation
東京
Related Report
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[Presentation] Comprehensive assessment of metabolic syndrome prevalence and its components among rural Bangladeshi women.
Author(s)
Akter S, Jesmin S, Shimojo N, Islam MM, Zaedi S, Yamaguchi N, Moroi M, Kimura S, Okazaki O, Hiroe M, Kawano S, Akashi H, Mizutani T
Organizer
2013 overseas scientific research Festa
Place of Presentation
東京
Related Report