| Project/Area Number |
25330041
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Statistical science
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| Research Institution | Jichi Medical University |
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Principal Investigator |
Mieno Makiko 自治医科大学, 医学部, 准教授 (60464707)
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| Co-Investigator(Kenkyū-buntansha) |
TANAKA Noriko 国立国際医療研究センター, 臨床研究センター医療情報解析研究部, 医学統計研究室長 (10376460)
ARAI Tomio 東京都健康長寿医療センター, 東京都健康長寿医療センター研究所, 病理診断科部長 (20232019)
SAWABE Motoji 東京医科歯科大学, 大学院保健衛生学研究科, 教授 (30196331)
ISHIKAWA Shizukiyo 自治医科大学, 医学教育センター, 教授 (70306140)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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| Keywords | アウトカム / 誤分類 / 死因 / 死亡診断書 / 病理解剖 / リスク推定 / アウトカム誤分類 / 生存時間解析 / 競合リスク / 病理診断 |
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| Outline of Final Research Achievements |
We evaluated the accuracy for major underlying cause of deaths (cancer, heart disease, and pneumonia) reported on death certificates compared with a reference standard of pathologist assessment based on autopsy data and clinical records. The concordance rate for cancer was relatively high (81%), but low for pneumonia (9%). Researchers should be aware of the accuracy of the cause of death data from death certificates used as research resources, especially for cases of elderly patients with pneumonia. We performed the sensitivity analysis and attempted the extension of multinomial logistic regression analysis for misclassified competing outcomes.
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