| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Outline of Final Research Achievements |
Since two hundred millions people are using arsenic-polluted well water for drinking, a large number of people develop arsenic poisoning including skin cancer and neural diseases. Although it is a vitally important problem in the world, there is no effective method for prediction, prevention, diagnosis and therapy. Our fieldwork analysis on arsenic-polluted area in Bangladesh and experimental analysis in our laboratory found that the amount of Placental Growth Factor (PlGF) protein was increased in urine of people who are drinking arsenic-polluted well water and also elucidated the mechanism of arsenic-mediated skin cancer development via PlGF.
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