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Efficacy and safety evaluation of new innovative gas phase sterilization technology for nucleolytic degradation

Research Project

Project/Area Number 25340071
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Environmental engineering and reduction of environmental burden
Research InstitutionKyushu University

Principal Investigator

OKAZAKI TOSHIHIKO  九州大学, 学内共同利用施設等, 研究員 (90529968)

Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2015: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Keywords滅菌・核酸分解装置 / ガス滅菌装置 / 医療機器 / 再生医療 / 新規滅菌機器 / 核酸分解装置
Outline of Final Research Achievements

We've developed innovative technology as the catalytic reaction type mixed gas generating system using methanol as a raw material, (Biovector, pat.no.5463378) And we have achieved very interesting evidence toward two major theme to be elucidated in this period (FY 2013-2015). Firstly as efficacy evaluation of sterility and nucleic acid degradation. Secondary an exhaust gas after catalyzed treatment showed residual harmful components below stipulated value, resulted in safety of Biovector, also confirmed using cultured cell with gas exposure test. In addition, we successful elucidated action mechanism of Biovector, that is, we proved specific 3 ingredients key factors that contribute to the results in the sterilization and nucleolytic degradation effect of Biovector, and to work as synergistic action of these components. We will step forward to develop Biovector as practical clinical apparatus as the future extended application.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (6 results)

All 2015 2014

All Presentation (6 results) (of which Int'l Joint Research: 1 results)

  • [Presentation] DNA-RNAフリー滅菌システム2015

    • Author(s)
      岡崎利彦、鈴木康士
    • Organizer
      日本内視鏡外科学会
    • Place of Presentation
      大阪国際会議場
    • Year and Date
      2015-12-10
    • Related Report
      2015 Annual Research Report
  • [Presentation] 革新的新規気相式核酸分解・滅菌装置の開発2015

    • Author(s)
      岡崎利彦
    • Organizer
      ARO協議会 第3回学術集会
    • Place of Presentation
      東京大学 伊藤国際学術研究センター
    • Year and Date
      2015-09-18
    • Related Report
      2015 Annual Research Report
  • [Presentation] Development of innovative gas phase sterilization technology for nucleolytic degradation2015

    • Author(s)
      TOSHIHIKO OKAZAKI
    • Organizer
      IUPESM World Congress 2015
    • Place of Presentation
      Metro Toronto Convention Centre, Toronto
    • Year and Date
      2015-06-07 – 2015-06-12
    • Related Report
      2014 Research-status Report
  • [Presentation] Development of innovative gas phase sterilization technology for nucleolitic degradeation2015

    • Author(s)
      T.Okazaki
    • Organizer
      World Congress on Medical Physics and Biomedical Engineering
    • Place of Presentation
      Toronto, Canada
    • Year and Date
      2015-06-07
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 革新的新規気相式核酸分解・滅菌装置の開発2015

    • Author(s)
      岡崎利彦
    • Organizer
      第14回日本再生医療学会総会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2015-03-19 – 2015-03-21
    • Related Report
      2014 Research-status Report
  • [Presentation] 新規気相式核酸分解・滅菌装置の開発2014

    • Author(s)
      岡崎利彦
    • Organizer
      生体医工学シンポジウム2014(東京)
    • Place of Presentation
      東京農工大学 小金井キャンパス
    • Year and Date
      2014-09-26 – 2014-09-27
    • Related Report
      2014 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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