To Evaluate positive correlation between bio-accumulation of POPs and pathological significant changes using stranded cetaceans in Japan.

• Project/Area Number: 25340105
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Environmental risk control and evaluation
• Research Institution: National Museum of Nature and Science, Tokyo
• Principal Investigator: TAJIMA YUKO 独立行政法人国立科学博物館, 動物研究部, 研究員 (00450635)
• Co-Investigator(Renkei-kenkyūsha): YAMADA TADASU 独立行政法人国立科学博物館, 動物研究部, 名誉研究員 (70125681) ; ISOBE TOMOHIKO 愛媛大学, 沿岸環境科学研究センター, 上級研究員 (50391066)
• Project Period (FY): 2013-04-01 – 2017-03-31
• Project Status: Completed (Fiscal Year 2016)
• Budget Amount: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000); Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000); Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000); Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
• Keywords: 病理 / ストランディング / 環境汚染物質 / POPs / 日和見感染症 / 生物濃縮 / リスク評価 / ヘルスアセスメント / リスクファクター / 病理学 / 内分泌器官 / 寄生虫 / 絶滅危惧種 / 寄生虫感染症 / スナメリ / 臭素系難燃剤 / 真菌症 / リスクファクター評価 / 汚染実態 / スジイルカ

Outline of Final Research Achievements

Analysis on POPs and pathological investigation were done on 33 melon-headed whales mass-stranded along the pacific coast in Japan on April, 2015. We compared these results with those of 32 melon-headed whales mass-stranded on March, 2011 in Japan and are planning to publish them. Summary of pathological research on 44 Stejneger's beaked whales stranded along the coast of the Sea of Japan during 12 years have been published. Therefore, we can try to detect the positive correlation between bio-accumulation of POPs and pathological findings in Stejneger's beaked whales too. A case report of Lobomycosis in an Indo-Pacific bottlenosed dolphin were published, however we did not detect the positive correlation between bio-accumulation of POPs and pathological findings.We joined in conservation research project on Ganges river dolphins (IUCN status; endangered) and then dissected dolphins and discuss on future plan at Patna university, India.

Research Products

• [Journal Article] Polybronimated diphenyl ethers (PBDEs) and their hydroxylated and nethoxylated analogues in the blood of harbor, Dall’s and finless porpoises from the Japanese coastal waters. (2016)
  • Author(s): Ochiai, M., Nomiyama, K., Isobe, T., Yamada, T. K., Tajima, Y., Matsuda, A., Shiozaki, A., Matsuishi, T., Amano, M., Iwata, M. and Tanabe, S.
  • Journal Title: Marine Environmental Research Volume: 2016 Pages: 1-9
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] 富山湾における鯨類の記録2015 (2016)
  • Author(s): 南部久男、関東雄、田島木綿子、山田格
  • Journal Title: 富山市科学博物館研報 Volume: 40 Pages: 99-101
  • Acknowledgement Compliant
• [Journal Article] Polybrominated diphenyl ethers (PBDEs) and their hydroxylated and methoxylated analogues in the blood of harbor, Dall's and finless porpoises from the Japanese coastal waters. (2016)
  • Author(s): Ochiai, M., K. Nomiyama, T. Isobe, T. K. Yamada, Y. Tajima, T. Matsuishi, M. Amano, H. Iwata, S. Tanabe
  • Journal Title: Marine Environmental Research. Volume: in press
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Toxic identification and evaluation of androgen receptor antagonistic activities in acid-treated liver extracts of high-trophic level wild animals from Japan. (2015)
  • Author(s): Misaki, K., G. Suzuki, N. M. Tue, S. Takahashi, M. Someya, H. Takigami, Y. Tajima, T. K. Yamada, M. Amano, T. Isobe and S. Tanabe
  • Journal Title: Environmental Science & Technology. Volume: 49(19) Issue: 19 Pages: 11840-11848
  • DOI: 10.1021/acs.est.5b02288
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] 野生動物の年齢を知る-方法と意義- (2015)
  • Author(s): 田島木綿子・山田格・小池裕子・粕谷俊雄
  • Journal Title: 哺乳類科学 Volume: 55 Pages: 89-91
  • Acknowledgement Compliant
• [Journal Article] A case of Indo-Pacific bottlenose dolphin (Tursiops aduncus) with lobomycosis-like lesions in Kagoshima, Japan. (2015)
  • Author(s): Tajima, Y., Sasaki, K., Kashiwagi, N. and Yamada, T. K.
  • Journal Title: J. Vet. Med. Sci. Volume: on line Pages: 00-00
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Pathological findings and probable causes of the death of Stejneger’s beaked whales (<i>Mesoplodon stejnegeri</i>) stranded in Japan from 1999 and 2011 (2015)
  • Author(s): Tajima, Y., Maeda, K. and Yamada, T. K.
  • Journal Title: Journal of Veterinary Medical Science Volume: 77 Issue: 1 Pages: 45-51
  • DOI: 10.1292/jvms.13-0454
  • NAID: 130004699214
  • ISSN: 0916-7250, 1347-7439
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] An ectoparasite and epizoite from a western gray whale (Eschrichtius robustus) stranded on Tomakomai, Hokkaido, Japan. (2014)
  • Author(s): Murase, M., Tajima, Y., Okamoto, M., Matsuishi, T., Yamada, T.K., Asakawa, M
  • Journal Title: J. Rakuno Gakuen Univ. Volume: 38 Pages: 149-152
  • NAID: 110009751795
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] 鳥取県沿岸と周辺海域で記録された海洋動物（2012年～2013年）-鯨類、鰭脚類、ウミガメ類、およびアカマンボウ目魚類について-. (2014)
  • Author(s): 一澤 圭、林 耕介、小笠原淳子、田島木綿子、上野真太郎、石原 孝、川上 靖、山田 格.
  • Journal Title: 鳥取県立博物館研究報告 Volume: 51 Pages: 59-65
  • Acknowledgement Compliant
• [Journal Article] 比較解剖学の過去、現在、未来 (2014)
  • Author(s): 田島木綿子、山田 格、関谷伸一、小泉政啓.
  • Journal Title: 哺乳類科学 Volume: 54(1) Pages: 1-4
  • NAID: 130005471761
  • Acknowledgement Compliant
• [Journal Article] Accumulation of hydroxylated polychlorinated biphenyls (OH-PCBs) and implications for PCBs metabolic capacities in three porpoise species. (2013)
  • Author(s): Ochiai, M., Nomiyama, K., Isobe, T., Mizukawa, H., Yamada, T. K., Tajima, Y., Matsuishi, T., Amano, M. and Tanabe, S.
  • Journal Title: Chemosphere Volume: 92(7) Pages: 803-810
  • Peer Reviewed
• [Journal Article] Two genetically distinct stocks in Baird’s beaked whale (Cetacea: Ziphiidae) (2013)
  • Author(s): Kitamura, S., Matsuishi, T., Yamada, T. K., Tajima, Y., Ishikawa, H., Tanabe, S., Nakagawa, H., Uni, Y. and Abe, S.
  • Journal Title: Marine Mammal Science Volume: 29 Issue: 4 Pages: 755-766
  • DOI: 10.1111/j.1748-7692.2012.00607.x
  • Peer Reviewed
• [Journal Article] Levels and temporal trends of brominated flame retardants and organochlorine POPs in melon-headed whales from Japan. (2013)
  • Author(s): Isobe, T., Sugimoto, R., Amano, M., Tajima, Y., Yamada, T. K. and Tanabe, S.
  • Journal Title: Organohalogen Compounds Volume: 75 Pages: 192-195
  • Peer Reviewed
• [Journal Article] Shimizu Y, Ohishi K, Suzuki R, Tajima Y, Yamada T, Kakizoe Y, Bando T, Fujise Y, Taru H, Maruyama T and Maruyama T. Amino acid sequence vaiations of signaling lymphocyte activation molecule and mortality causd by morbillivirus infection in cetaceans. (2013)
  • Author(s): Shimizu Y, Ohishi K, Suzuki R, Tajima Y, Yamada T, Kakizoe Y, Bando T, Fujise Y, Taru H, Maruyama T and Maruyama T.
  • Journal Title: Microbiological Immunology Volume: 57 Pages: 624-632
  • Peer Reviewed
• [Presentation] Infectious Diseases of Marine mammals in Asia. (2016)
  • Author(s): Tajima Y. and Yamada TK..
  • Organizer: 16th Annual Conference of Asian Society of Conservation Medicine.
  • Place of Presentation: 台北市、台湾
  • Year and Date: 2016-10-21
  • Int'l Joint Research
• [Presentation] 海の哺乳類の骨盤について． (2016)
  • Author(s): 田島木綿子
  • Organizer: 日本哺乳類学会2016年度大会（筑波）
  • Place of Presentation: 筑波大学学生会館（茨城県、つくば市）
  • Year and Date: 2016-09-21
  • Invited
• [Presentation] 茨城県鉾田市に集団座礁したカズハゴンドウ（Peponocephala electra）の胃内容物 (2016)
  • Author(s): 松田純佳，山田格，田島木綿子，松石隆.
  • Organizer: 日本セトロジー研究会第27回（寺泊）大会
  • Place of Presentation: 長岡市寺泊文化センター（新潟県、長岡市）
  • Year and Date: 2016-06-25
• [Presentation] 茨城県に集団座礁したカズハゴンドウPeponocephala electraに残留するPCBs，OH-PCBsの脳内負荷量と母仔間移行. (2016)
  • Author(s): 落合真理，野見山 桂，磯部友彦，山田 格，田島木綿子，岩田久人，国末達也，田辺信介
  • Organizer: 日本セトロジー研究会第27回（寺泊）大会
  • Place of Presentation: 長岡市寺泊文化センター（新潟県、長岡市）
  • Year and Date: 2016-06-25
• [Presentation] 北海道沿岸に座礁した鯨類における有機ハロゲン化合物の蓄積特性. (2016)
  • Author(s): 江頭佳奈，磯部友彦，落合真理，松石 隆，松田純佳，山田 格，田島木綿子，田辺信介，国末達也
  • Organizer: 日本セトロジー研究会第27回（寺泊）大会
  • Place of Presentation: 長岡市寺泊文化センター（新潟県、長岡市）
  • Year and Date: 2016-06-25
• [Presentation] カマイルカ胸・腰神経後枝の観察. (2016)
  • Author(s): 時田幸之輔，関谷伸一，田島木綿子，山田 格.
  • Organizer: 日本セトロジー研究会第27回（寺泊）大会
  • Place of Presentation: 長岡市寺泊文化センター（新潟県、長岡市）
  • Year and Date: 2016-06-25
• [Presentation] ロボマイコーシス様皮膚疾患が認められた鹿児島県錦江湾で漂着したミナミハンドウイルカの１例. (2016)
  • Author(s): 田島木綿子，佐々木恭子，柏木伸幸，山田 格.
  • Organizer: 日本セトロジー研究会第27回（寺泊）大会
  • Place of Presentation: 長岡市寺泊文化センター（新潟県、長岡市）
  • Year and Date: 2016-06-25
• [Presentation] 2016年4月，伊東市に漂着した幼若なコククジラ. (2016)
  • Author(s): 山田 格，田島木綿子，浅川 弘.
  • Organizer: 日本セトロジー研究会第27回（寺泊）大会
  • Place of Presentation: 長岡市寺泊文化センター（新潟県、長岡市）
  • Year and Date: 2016-06-25
• [Presentation] 漂着専門委員会報告；日本沿岸のストランディングレコード2015. (2016)
  • Author(s): 石川創，田島木綿子，石井雅之，山田格，小原王明.
  • Organizer: 日本セトロジー研究会第27回（寺泊）大会
  • Place of Presentation: 長岡市寺泊文化センター（新潟県、長岡市）
  • Year and Date: 2016-06-25
• [Presentation] 超音波診断装置による日本沿岸のスナメリの卵胞サイズ測定.カマイルカ胸・腰神経後枝の観察. (2016)
  • Author(s): 岩橋佑佳，近藤圭佑，天野雅男，田島木綿子.
  • Organizer: 日本セトロジー研究会第27回（寺泊）大会
  • Place of Presentation: 長岡市寺泊文化センター（新潟県、長岡市）
  • Year and Date: 2016-06-25
• [Presentation] Pathological findings and probable causes of the death of Stejneger’s beaked whales (Mesoplodon stejnegeri) stranded in Japan from 1999 to 2011. (2015)
  • Author(s): Tajima, Y., K. Maeda, and T. K. Yamada
  • Organizer: 21st Biennial Conference on the Biology of Marine Mammals.
  • Place of Presentation: Hilton San Francisco Union Square, San Francisco,USA.
  • Year and Date: 2015-12-13
  • Int'l Joint Research
• [Presentation] Stranding Information on Cetaceans in Japan. (2015)
  • Author(s): Tajima, Y., M. Ishii, H. Ishikawa and T. K. Yamada
  • Organizer: IWC Workshop on Investigations of Large Mortality Events, Mass Stranding, and International Stranding Response.
  • Place of Presentation: Greater Farallones National Marine Sanctuary Office. San Francisco, CA, USA.
  • Year and Date: 2015-12-11
  • Int'l Joint Research / Invited
• [Presentation] Introductory talk and general biology: our understanding on the sperm whale (Physeter macrocephalus). (2015)
  • Author(s): Yamada, T. K., and Y. Tajima
  • Organizer: 8th International Conference on Conservation Medicine.
  • Place of Presentation: Yangon Zoological Garden, Yangon, Myanmar.
  • Year and Date: 2015-10-16
  • Int'l Joint Research / Invited
• [Presentation] PCBs, PBDEs and their hydroxylated metabolites in the brain of free-ranging toothed and baleen whales. (2014)
  • Author(s): Ochiai, M., Nomiyama, K., Isobe, T., Yamada, T. K., Tajima, Y., Makara, M., Amano, M., Matsuishi, T., Iwata, H. and Tanabe, S.
  • Organizer: 6th Bilateral Seminar Italy-Japan "Physical and chemical impacts on marine organisms: supporting blue growth in meaningful umutual symbiosis with the marine environment.
  • Place of Presentation: Palermo city, Italy
  • Year and Date: 2014-11-08 – 2014-11-13
• [Presentation] 野生哺乳類の年齢を知る (2014)
  • Author(s): 田島木綿子, 山田 格.
  • Organizer: 日本哺乳類学会年次大会
  • Place of Presentation: 京都大学、京都
  • Year and Date: 2014-09-15 – 2014-09-19
• [Presentation] 日本沿岸のストランディングレコード2013 (2014)
  • Author(s): 石川 創, 田島木綿子, 山田 格, 小原王明.
  • Organizer: 日本セトロジー研究会年次大会
  • Place of Presentation: 愛媛大学、松山市
  • Year and Date: 2014-05-22 – 2014-05-23
• [Presentation] 2014年3月漂着したオウギハクジラ二例について（予報） (2014)
  • Author(s): 山田 格, 田島木綿子, 長澤一雄, 一澤 圭.
  • Organizer: 日本セトロジー研究会年次大会
  • Place of Presentation: 愛媛大学、松山市
  • Year and Date: 2014-05-22 – 2014-05-23
• [Presentation] A case report of ‘Lobomycosis-like disease’ in a stranded indo-pacific bottlenose dolphin, Tursiops aduncus in Kinko-wan, Kaghoshima, Japan. (2014)
  • Author(s): Tajima, Y., Sasaki, K., Kashiwagi, N. and Yamada, T. K.
  • Organizer: 45th Annual meeting of International Association for Aquatic Animal Medicine (IAAAM)
  • Place of Presentation: Gold coast Sea World, Gold coast, Australia.
  • Year and Date: 2014-05-17 – 2014-05-21
• [Presentation] A review of stranding survey in Japan. (2013)
  • Author(s): Tajima Y and Yamada TK.
  • Organizer: Annual meeting of International Association for Aquatic Animal Medicine
  • Place of Presentation: Sausalito, CA, USA.
  • Invited
• [Presentation] Preliminary report of a stranded Indo-Pacific bottlenose dolphin (Tursiops aduncus) with Lobomycosis-like skin lesion, in Kinko-wan, Kagoshima, Kyushu, Japan. (2013)
  • Author(s): Tajima, Y., K. Sasaki, N. Kashiwagi and T. K. Yamada.
  • Organizer: Scientific Committee of the International Whaling Commission
  • Place of Presentation: Jeju Island, Republic of Korea.
  • Invited
• [Presentation] Genetic Population Structure of Finless Porpoise in Japanese Coastal Waters. (2013)
  • Author(s): Aizu, M., S. Nishida, J. Kusumi, Y. Tajima, T. K. Yamada, M. Amano and K. Araya.
  • Organizer: Scientific Committee of the International Whaling Commission
  • Place of Presentation: Jeju Island, Republic of Korea.
  • Invited
• [Presentation] Cetacean morphology. How far they are derived and how far they are generalized? (2013)
  • Author(s): T.K. Yamada and Yuko T.
  • Organizer: Combined Conference 2013- One health in Aia Pacific
  • Place of Presentation: Singapore
  • Invited
• [Book] 「イルカ・クジラを取り巻く海の環境問題-海ごみ-」p3-4 in Flipper 2016 Summer (2016)
  • Author(s): 山口ひろみ、田島木綿子他
  • Total Pages: 14
  • Publisher: アイサーチジャパン
• [Book] 「イルカのひみつ・クジラのふしぎ」p3-10 (2016)
  • Author(s): 山口ひろみ、田島木綿子
  • Total Pages: 14
  • Publisher: アイサーチジャパン
• [Book] イルカ・クジラを取り巻く海の環境問題-海岸に漂着したイルカ・クジラからわかること- p7-10 in Flipper 2016 Winter (2016)
  • Author(s): 山口ひろみ、田島木綿子他
  • Total Pages: 18
  • Publisher: アイサーチジャパン
• [Book] 続イルカ・クジラ学(村山司・鈴木美和・吉岡基（編）) (2015)
  • Author(s): 前田義秋、佐伯宏美、村山司、鈴木美和、佐々木基樹、田島木綿子、村上瑞季、上田貴久、山本友紀子、森恭一、関口圭子、靑木かがり
  • Total Pages: 198
  • Publisher: 東海大学出版部
• [Book] 続イルカ・クジラ学 (2015)
  • Author(s): 村山司・鈴木美和・吉岡基 編著
  • Total Pages: 198
  • Publisher: 東海大学出版部
• [Remarks] ストランディング速報
  • URL: http://svrsh1.kahaku.go.jp/marmam/
• [Remarks] 海棲哺乳類図鑑
  • URL: http://svrsh2.kahaku.go.jp/pictorial_book/
• [Funded Workshop] 8th International Conference on Conservation Medicine. (2015)
  • Place of Presentation: Yangon Zoological Garden, Yangon, Myanmar.
  • Year and Date: 2015-10-16