| Project/Area Number |
25350063
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Home economics/Human life
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| Research Institution | Kanazawa Medical University |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
OIKAWA Yosaburo 金沢医科大学, 医学部, 講師 (10139785)
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| Research Collaborator |
HORI Kiyoe
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| Project Period (FY) |
2013-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2016: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2015: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 日本脳炎 / 日本脳炎ウイルス / 感染症 / コガタアカイエカ / アルボウイルス / フラビウイルス |
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| Outline of Final Research Achievements |
Japanese encephalitis virus (JEV) is a flavivirus and is responsible for over 30,000 annual cases of encephalitis worldwide, with a mortality rate of approximately 30%. Therefore, it is important to check the distribution of JEV in fields, although recently, the number of Japanese encephalitis (JE) cases has been approximately five per year in Japan. We report the seasonal dynamics of mosquitoes between 2013 and 2016 in Ishikawa Prefecture, Japan. We collected 27,422 female adult mosquitoes, 98% of which were classified as Culex tritaeniorhynchus Giles. We identified JEV genomic RNA belonging to genotype 1 among the homogenate of Cx. tritaeniorhynchus collected during our study using reverse transcription-polymerase chain reaction and nucleotide sequencing methods. Our results indicated that mosquito vectors for JEV are distributed not only in areas in Ishikawa but also throughout Japan and suggest that we must be careful regarding JEV outbreaks in Japan in the future.
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