Studies on the suppression of allergy by traditional seaweed dishes especially focussing on chlorophyll c2

• Project/Area Number: 25350109
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Eating habits
• Research Institution: Kyoto Kacho University
• Principal Investigator: Toyohara Masako 京都華頂大学, その他部局等, 教授 (50241211)
• Co-Investigator(Kenkyū-buntansha): TOYOHARA Haruhiko 京都大学(連合), 農学研究科(研究院), 准教授 (90183079)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Project Status: Completed (Fiscal Year 2015)
• Budget Amount: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000); Fiscal Year 2015: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2013: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
• Keywords: クロロフィルＣ２ / 褐藻 / 調理 / 抗アレルギー活性 / クロロフィルｃ２ / 海藻食 / アレルギー疾患 / 海藻 / 伝統食 / 抗アレルギー作用

Outline of Final Research Achievements

Suppression of allergy reaction by taking brown algae as dishes including chlorophyll c2 having anti-allergic activity was validated. The content of chlorophyll c2 in dried seaweed was lower than raw seaweed, but chlorophyll c2 could be taken by reducing the heating and cooking time. On the other hand, no significant relationship between seaweed feeding and anti-allergic effect was not recognized according to the hearing investigation in fishing village.

Research Products

• [Journal Article] The iron content and ferritin contribution in fresh, dried, and toasted nori, Pyropia yezoensis. (2015)
  • Author(s): Masuda T., Yamamoto A., & Toyohara H.
  • Journal Title: Biosci., Biotechnol. Biochem. Volume: 79 Issue: 1 Pages: 74-81
  • DOI: 10.1080/09168451.2014.968087
  • NAID: 120005657918
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Studies on anti-allergic activity of Saegassum horneri estract. (2014)
  • Author(s): H. Yoshioka, M. Ishida, K. Nishi, H. Oda, H. Toyohara, T. Sugawara.
  • Journal Title: J. Func. Foods. Volume: 10 Pages: 154-160
  • Peer Reviewed
• [Journal Article] A high-throughput screen for inhibitors of the prolyl isomerase, Pin1, identifies a seaweed polyphenol that reduces adipose cell differentiation. (2014)
  • Author(s): Mori T, Hidaka M, Ikuji H, Yoshizawa I, Toyohara H, Okuda T, Uchida C, Asano T, Yotsu-Yamashita M, Uchida T
  • Journal Title: Biosci. Biotechnol. Biochem. Volume: 78 Issue: 5 Pages: 832-838
  • DOI: 10.1080/09168451.2014.905189
  • Peer Reviewed / Open Access
• [Presentation] Studies on Japanese traditional seaweed dishes as functional foods (2015)
  • Author(s): 豊原容子
  • Organizer: 12th Asian Congress of Nutrition
  • Place of Presentation: Yokohama,Japan
  • Year and Date: 2015-05-16
  • Int'l Joint Research
• [Presentation] Studies on Japanese traditional seaweed dishes as functional foods (2015)
  • Author(s): Masako Toyohara, Haruhiko Toyohara, Hisashi Yoshioka, Akira Kamata, Takuya Sugahara
  • Organizer: 12th Asian Congress of Nutrition
  • Place of Presentation: Yokohama,Japan
  • Year and Date: 2015-05-14 – 2015-05-18
• [Presentation] 海藻伝統食の探索
  • Author(s): 豊原容子、塩田二三子
  • Organizer: 日本調理科学会平成２５年大会
  • Place of Presentation: 奈良女子大学