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Development of nutritional therapy that contributes to prevention and treatment of exercise induced hemolysis

Research Project

Project/Area Number 25350129
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Eating habits
Research InstitutionKyoto Prefectural University

Principal Investigator

Kobayashi Yukiko  京都府立大学, 生命環境科学研究科, 助教 (10381930)

Project Period (FY) 2013-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2013: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Keywords運動誘発性溶血 / スポーツ貧血 / 鉄代謝 / 酸化ストレス / 運動負荷ラット / キシロオリゴ糖 / 栄養療法 / 鉄欠乏 / 低栄養 / 栄養欠乏 / 低タンパク / 高強度運動 / 運動性溶血 / セロビオン酸 / ランニング / オリゴ糖 / スポーツ性貧血 / 高強度運動負荷
Outline of Final Research Achievements

We examined the onset mechanism of sports anemia in response to exercise induced hemolysis and iron deficiency and searched for effective nutrients for exercise induced hemolysis. We performed acute and chronic high intensity exercise tolerance tests of rats under various conditions and compared physiological and iron metabolic fluctuations. As a result, it was shown that exercise induced hemolysis model rats can be prepared. Because intake of uronic acid bonded xylooligosaccharide, which has been shown to be useful for prevention and improvement of iron deficiency anemia, has led to suppression of hemolysis inducing factors such as lactic acid production and muscle damage in exercise induced hemolytic model rats, we suggested that uronic acid bonded xylooligosaccharide is one of nutrient components contributing to the prevention of sports anemia.

Report

(6 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (2 results)

All 2013

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (1 results)

  • [Journal Article] Assessment of daily food and nutrient intake in Japanese type 2 diabetes mellitus patients using dietary reference intakes.2013

    • Author(s)
      Kobayashi Y, Kuwahata M, et al.
    • Journal Title

      Nutrients

      Volume: 5 Pages: 2276-2288

    • DOI

      10.4137/nmi.s13668

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Presentation] 高強度運動負荷ラットに対するウロン酸結合キシロオリゴ糖摂取の効果2013

    • Author(s)
      小林ゆき子、南川聖月、桑波田雅士、青井渉、木戸康博
    • Organizer
      第7回日本スポーツ栄養研究会学術総会
    • Place of Presentation
      神奈川県立保健福祉大学
    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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