Study on mechanisms of memory decline by magnetoencephalography
Project/Area Number |
25350516
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Biomedical engineering/Biomaterial science and engineering
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Research Institution | Hokkaido University |
Principal Investigator |
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Co-Investigator(Kenkyū-buntansha) |
OTSUKI Mika 北海道大学, 大学院保健科学研究院, 准教授 (10372880)
|
Project Period (FY) |
2013-04-01 – 2016-03-31
|
Project Status |
Completed (Fiscal Year 2015)
|
Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2015: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2013: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
|
Keywords | 短期記憶 / 加齢 / α波脳律動 / 脳磁計 / 初頭性・新近性効果 / 初頭性効果・新近性効果 |
Outline of Final Research Achievements |
Magnetoencepahlograms during the performance of short-term memory tasks were compared between participants in their twenties (young) and sixties (aged). During the memorization of sequentially-presented memory items, displayed on a screen, the alpha-rhythm (8-13 Hz) amplitudes of young participants increased in corresponding with memory encoding process, while that of aged participants conversely decreased. Source estimation of the alpha-rhythm suggested that its increase was due to active inhibition of task-irrelevant visual inputs, and that aging may disable this active inhibition, thus causing memory decline.
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Report
(4 results)
Research Products
(192 results)
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[Journal Article] Amplitude modulation of alpha-band rhythm caused by mimic collision: MEG study2013
Author(s)
Yokosawa, K., Watanabe, T., Kikuzawa, D., Aoyama, G., Takahashi, M., & Kuriki, S.
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Journal Title
Engineering in Medicine and Biology Society (EMBC)
Volume: 1
Pages: 6187-6190
DOI
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Peer Reviewed
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[Journal Article] Magnetic displacement force and torque on dental keepers in the static magnetic field of a magnetic resonance scanner2013
Author(s)
Omatsu, M., Obata, T., Minowa, K., Yokosawa, K., Inagaki, E., Ishizaki, K., Shibayama, K., & Yamamoto, T.
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Journal Title
Journal of Magnetic Resonance Imaging
Volume: 1
Issue: 6
Pages: 1481-1486
DOI
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Peer Reviewed
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[Journal Article] Cognitive impairment and cortical degeneration in neuromyelitis optica.2012
Author(s)
Saji E, Arakawa M, Yanagawa K, Toyoshima Y, Yokoseki A, Okamoto K, Otsuki M, Akazawa K, Kakita A, Takahashi H, Nishizawa M, Kawachi I.
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Journal Title
Ann Neurol.
Volume: 73
Issue: 1
Pages: 65-76
DOI
Related Report
Peer Reviewed
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[Presentation] 前頭葉と理解障害2015
Author(s)
大槻美佳
Organizer
第39回日本高次脳機能障害学会
Place of Presentation
ベルサール渋谷ファースト(東京都渋谷区)
Year and Date
2015-12-10
Related Report
Invited
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[Presentation] 言語の神経心理学2015
Author(s)
大槻美佳
Organizer
第39回日本神経心理学会
Place of Presentation
札幌市教育文化会館(北海道札幌市)
Year and Date
2015-09-10
Related Report
Invited
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[Presentation] 「疑問一挙解決!」2015
Author(s)
橋本竜作、中川賀嗣、大槻美佳
Organizer
第39回日本神経心理学会
Place of Presentation
札幌市教育文化会館(北海道札幌市)
Year and Date
2015-09-10
Related Report
Invited
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[Presentation] 語義失語の症状と経過2015
Author(s)
小野大輔、金藤公人、大槻美佳、日野美貴、斎藤匠真
Organizer
第39回日本神経心理学会
Place of Presentation
札幌市教育文化会館(北海道札幌市)
Year and Date
2015-09-10
Related Report
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[Presentation] 原発性進行性失語2015
Author(s)
大槻美佳
Organizer
第56回日本神経学会学術大会
Place of Presentation
朱鷺メッセ(新潟県新潟市)
Year and Date
2015-05-20
Related Report
Invited
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[Presentation] 失構音を伴ったLPAの1例2014
Author(s)
佐藤玲子、竹内茂伸、井後雅之、大槻美佳
Organizer
第38回高次脳機能障害学会
Place of Presentation
仙台
Year and Date
2014-11-28 – 2014-11-29
Related Report
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[Presentation] 発話の神経基盤2014
Author(s)
大槻美佳
Organizer
第4回日本言語聴覚士協会九州地区学術集会大会
Place of Presentation
大分
Year and Date
2014-10-11 – 2014-11-12
Related Report
Invited
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[Presentation] 短期記憶障害とその対応2014
Author(s)
大槻美佳
Organizer
高次脳機能障害学会 2014年 夏期教育研修講座
Place of Presentation
名古屋
Year and Date
2014-07-20
Related Report
Invited
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[Book] Recent Developments and New Directions in Soft Computing2014
Author(s)
T. Yamanoi, Y. Tanaka, M. Otsuki, S. Ohnishi, T. Yamazaki, M. Sugeno (Eds.: Zadeh, L.A., Abbasov, A.M., Yager, R.R., Shahbazova, S.N., Reformat, M.Z.)
Publisher
Springer International Publishing Switzerland
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