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Development of Doppler optical cohrence tomography system for real-time analysis of ovary function

Research Project

Project/Area Number 25350519
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Biomedical engineering/Biomaterial science and engineering
Research InstitutionYamagata University

Principal Investigator

watanabe yuuki  山形大学, 理工学研究科, 准教授 (00333328)

Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2015: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2013: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
KeywordsOCT / Doppler OCT / GPU / 卵巣機能 / 光干渉断層計
Outline of Final Research Achievements

The application of Dppler optical coherence tomography (OCT) was stduied for noninvasive analysis of follicular development in mouse ovaries. We discovered time-varying OCT signals at the oocytes that differentiated them from surrounding tissues. These signals were clearly enhanced by interframe intensity-based Doppler OCT techniques. We could estimate the 3D distribution of oocytes in the ovary. The OCT technology was effective in analyzing the development of follicles and oocytes in ovaries

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (11 results)

All 2015 2014 2013

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (10 results) (of which Int'l Joint Research: 1 results)

  • [Journal Article] Optical coherence tomography imaging for analysis of follicular development in ovarian tissue2015

    • Author(s)
      Watanabe Y., Takakura K., Kurotani R., Abe H.
    • Journal Title

      Applied Optics

      Volume: 54 Issue: 19 Pages: 6111-6115

    • DOI

      10.1364/ao.54.006111

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Presentation] Analysis of follicular development in ovary using optical coherence tomography2015

    • Author(s)
      Yuuki Watanabe, Kei Takakura, Reiko Kurotani, Hiroyuki Abe
    • Organizer
      Optics in the Life Sciences Congress
    • Place of Presentation
      Pinnacle Vancouver Harbourfront ホテル(カナダ)
    • Year and Date
      2015-04-12
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] OCT を用いたマウス卵巣内卵胞のリアルタイム計測2014

    • Author(s)
      渡部 裕輝,高倉 啓,黒谷 玲子,阿部 宏之
    • Organizer
      日本光学会年次学術講演会 Optics & Photonics Japan 2014
    • Place of Presentation
      筑波大学東京キャンパス文京校舎
    • Year and Date
      2014-11-05 – 2014-11-07
    • Related Report
      2014 Research-status Report
  • [Presentation] GPU-OCT によるマウス卵巣機能のリアルタイム画像化システムの開発2014

    • Author(s)
      鎌田 あやね,渡部 裕輝,高倉 啓, 黒谷 玲子,阿部 宏之
    • Organizer
      日本光学会年次学術講演会 Optics & Photonics Japan 2014
    • Place of Presentation
      筑波大学東京キャンパス文京校舎
    • Year and Date
      2014-11-05 – 2014-11-07
    • Related Report
      2014 Research-status Report
  • [Presentation] GPU によるOCT 画像のリアルタイム数値分散補償の検討2014

    • Author(s)
      太田 拓実,渡部 裕輝
    • Organizer
      日本光学会年次学術講演会 Optics & Photonics Japan 2014
    • Place of Presentation
      筑波大学東京キャンパス文京校舎
    • Year and Date
      2014-11-05 – 2014-11-07
    • Related Report
      2014 Research-status Report
  • [Presentation] ドップラー光干渉断層画像化法を応用した高感度卵胞3次元イメージング2014

    • Author(s)
      高倉 啓, 黒谷玲子, 渡部裕輝, 阿部宏之
    • Organizer
      第32回日本受精着床学会総会
    • Place of Presentation
      ハイアット リージェンシー 東京
    • Year and Date
      2014-07-31 – 2014-08-01
    • Related Report
      2014 Research-status Report
  • [Presentation] ドップラー光干渉断層画像化技術を応用した3 次元卵胞イメージングシステムの開発2014

    • Author(s)
      高倉 啓, 黒谷玲子, 渡部裕輝, 阿部宏之
    • Organizer
      第55回日本卵子学会
    • Place of Presentation
      神戸国際会議場
    • Year and Date
      2014-05-17 – 2014-05-18
    • Related Report
      2014 Research-status Report
  • [Presentation] GPU Accelerated Correlation Mapping OCT for Real-Time Imaging of Microvasculature2013

    • Author(s)
      Yuuki Watanabe, Hiroshi Numazawa, and Dai Kamiyama
    • Organizer
      CLEO-PR & OECC/PS 2013
    • Place of Presentation
      京都国際会議場
    • Related Report
      2013 Research-status Report
  • [Presentation] PU-OCTによる実時間モーション補正を行うOCTアンジオグラフィの開発2013

    • Author(s)
      沼沢拡, 渡部裕輝
    • Organizer
      応用物理学会東北支部第68回学術講演会
    • Place of Presentation
      山形大学工学部
    • Related Report
      2013 Research-status Report
  • [Presentation] 光干渉断層画像化法を応用したマウス卵胞の非侵襲イメージングシステムの開発2013

    • Author(s)
      阿部宏之、高倉啓、坂原聖士、黒谷玲子、渡部裕輝
    • Organizer
      第31回日本受精着床学会総会
    • Place of Presentation
      別府国際コンベンションセンター
    • Related Report
      2013 Research-status Report
  • [Presentation] 光干渉断層画像化法を応用したマウス卵巣内卵胞の非侵襲的観察2013

    • Author(s)
      高倉 啓,栢本亮太,黒谷玲子,渡部裕輝,阿部宏之
    • Organizer
      第54 回日本哺乳動物卵子学会
    • Place of Presentation
      学術総合センター
    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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