| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Outline of Final Research Achievements |
We have conducted this research to develop polymer coating agents constructing material surfaces showing antithrombogenicity. As a raw material for such polymeric agents, we have focused on the use of end-functionalized vinyl polymers with plant-derived oligosaccharides. A method to prepare end-glycosylated polymers with well-defined structures in water has been developed in this study. Film-formation experiments by casting the solution of the end-glycosylated polymers on the silicone substrate and protein adhesion tests on the film-surface were demonstrated, suggesting that the polymer synthesized in this study has a potential as being applicable to polymeric agents providing material surfaces showing antithrombogenicity.
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