| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2015: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2014: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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| Outline of Final Research Achievements |
There are many polymers showing LCST-type phase transition behavior under physiological conditions. However, there is few polymers showing UCST-type phase transition behavior under the conditons. We have reported that poly citrulline polypeptide showed UCST-type behavior. In this study, we estimated effect of optical activity of the polypeptide on UCST-type solution behavior. CD spectra indicated that the polypeptide adopted a-helix conformation and form a bundle structure below phase separation temperature.
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