| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Outline of Final Research Achievements |
The purpose of this study was to develop a computer-aided detection (CADe) scheme for coronary artery stenoses on whole-heart coronary magnetic resonance angiography (MRA). Based on the curvatures and the lengths from beginning and bifurcations, the segmented arteries were classified according to the American Heart Association (AHA) classifications. The signal intensity at each voxel of centerline of the segmented artery was defined by the maximum signal intensity within a circle with a radius of 3 voxels centered at the voxel in the original MRA image. While tracing the centerline, the voxel with which the signal intensity showed rapid reduction was finally detected as arterial stenosis. Threshold levels for this detection were selected empirically at each AHA classification by taking into account the variations in the signal intensities for normal coronary artery. With our CADe scheme, a sensitivity of artery stenoses was 87.2% with 1.83 false positives (FPs) per patient.
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