| Project/Area Number |
25350601
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Rehabilitation science/Welfare engineering
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| Research Institution | Kagawa University |
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Principal Investigator |
TOUGE TETSUO 香川大学, 医学部, 教授 (80197839)
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| Co-Investigator(Kenkyū-buntansha) |
GO KEIRYU 岡山大学, 工学部, 教授 (30294648)
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| Co-Investigator(Renkei-kenkyūsha) |
IKEDA KAZUYO 香川大学, 医学部, 病院助教 (30592315)
KUME KODAI 香川大学, 医学部, 助教 (20592314)
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| Research Collaborator |
RI KI
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2015: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2014: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2013: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
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| Keywords | 経頭蓋脳磁気刺激 / 最大筋収縮 / 高齢者 / 認知機能訓練 / 運動機能訓練 / 事象関連電位 / 脳磁気刺激 / リハビリテーション / 認知機能 / 事象関連脳電位 / 経頭蓋磁気刺激 |
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| Outline of Final Research Achievements |
In eight healthy adult subjects, transcranial magnetic stimulation with the maximum voluntary muscle contraction (TMS with MVC) was performed intermittently for 40 minutes. Digit span and digit-symbol coding of Wechsler Adult Intelligence Scale－Third Edition, motor evoked potentials, pinching muscle force and multimodality event related potentials (ERP) were measured before and after TMS with MVC. As a result, in comparison with the placebo group using false magnetic stimulation, the test group employing real magnetic stimulation was improved recalling a series of numbers in inverse order (P<0.05), and tended to be increased pinching muscle force. Although the potential related to multimodality cognition of ERP did not differ between the groups, we need further analysis for each ERP component. As a conclusion, the present result suggests that TMS with MVC can improve muscle force and verbal memory function.
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