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Repetitive facilitative exercise synchronized with transcranial magnetic stimulation, neuromuscular electrical stimulation on functional recovery of hemiplegic upper limb

Research Project

Project/Area Number 25350605
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Rehabilitation science/Welfare engineering
Research InstitutionKagoshima University

Principal Investigator

Etoh Seiji  鹿児島大学, 医歯学域医学系, 講師 (70295244)

Co-Investigator(Kenkyū-buntansha) 川平 和美  鹿児島大学, 医歯学総合研究科, 客員研究員 (20117493)
下堂薗 恵  鹿児島大学, 医歯学域医学系, 教授 (30325782)
緒方 敦子  鹿児島大学, 医歯学域医学系, 助教 (40305123)
Project Period (FY) 2013-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords促通反復療法 / 経頭蓋磁気刺激 / 神経筋電気刺激 / 脳卒中 / リハビリテーション / 片麻痺上肢 / 片麻痺 / 電気刺激 / 振動刺激
Outline of Final Research Achievements

The aim of this study is to investigate whether multiple sessions of transcranial magnetic stimulation (TMS), neuromuscular electrical stimulation (NMES), and repetitive facilitative exercise (RFE) facilitated the recovery of hemiplegic upper-limb function in chronic stroke patients. The repetitive TMS (rTMS) was applied over the motor cortex of the unaffected hemisphere at a frequency of 1 Hz before RFE. NMES was delivered to stimulate the target muscle of the affected upper limb using a portable surface neuromuscular stimulator. The surface electrodes were arranged over the wrist extensors or extensor digitorum communis. Motor function of hemiplegic upper limb improved after rTMS, NMES and RFE. RFE synchronized TMS was also effective for recovery of upper limb function. These results indicate that combination of central nerve stimulation (TMS) and peripheral stimulation (NMES, RFE) may be effective for functional recovery of hemiplegic upper limb in stroke patients.

Report

(5 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (4 results)

All 2016 2014 2013

All Presentation (4 results)

  • [Presentation] 単発経頭蓋磁気刺激を同期させた促通反復療法により麻痺側手指機能が改善した脳卒中の1例2016

    • Author(s)
      衛藤誠二、下堂薗恵
    • Organizer
      第28回九州神経生理研究会
    • Place of Presentation
      伊王島ホテル(長崎県長崎市)
    • Year and Date
      2016-08-20
    • Related Report
      2016 Annual Research Report
  • [Presentation] 経頭蓋磁気刺激を同期させた促通反復療法による片麻痺上肢機能の改善2014

    • Author(s)
      衛藤誠二
    • Organizer
      日本リハビリテーション医学会学術集会
    • Place of Presentation
      名古屋市
    • Related Report
      2013 Research-status Report
  • [Presentation] Effect of the intensive rehabilitation on functional recovery and motor neuron excitability after stroke2014

    • Author(s)
      衛藤誠二
    • Organizer
      International conference of clinical neurophysiology
    • Place of Presentation
      ドイツ、ベルリン
    • Related Report
      2013 Research-status Report
  • [Presentation] 脳卒中片麻痺上肢の痙縮、機能回復とF波2013

    • Author(s)
      衛藤誠二
    • Organizer
      日本臨床神経生理学会学術集会
    • Place of Presentation
      高知市
    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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