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Sarcopenic dysphagia analyzed by computed tomography

Research Project

Project/Area Number 25350611
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Rehabilitation science/Welfare engineering
Research InstitutionYokohama City University

Principal Investigator

Wakabayashi Hidetala  横浜市立大学, 大学病院, 助教 (80508797)

Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywordsサルコペニア / 嚥下障害 / 摂食嚥下障害 / 栄養 / リハビリテーション / サルコペニア肥満
Outline of Final Research Achievements

The purpose of this study was to assess the association between skeletal muscle mass, activities of daily living (ADLs) and severe dysphagia in cancer patients. A nested case-control study was performed in 111 consecutive cancer patients with dysphagia who were prescribed speech therapy.
There were 86 men and 25 women (mean age, 70 years). The mean skeletal muscle index (SMI) was 5.68±1.74 cm2/m2 in men and 4.43±1.21cm2/m2 in women. The median Barthel Index score was 20. 33 were on non-oral feeding at discharge. Logistic regression analysis of the severity of dysphagia adjusted for age, sex, SMI, Barthel Index score, serum albumin, cancer type and stage, and vocal cord paralysis showed that SMI was associated independently with oral food intake at discharge. Barthel Index score showed a tendency to be associated with oral food intake.
Skeletal muscle mass is associated with severe dysphagia in cancer patients. ADLs show a tendency to be associated with severe dysphagia.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (13 results)

All 2016 2015 2014 2013 Other

All Journal Article (4 results) (of which Peer Reviewed: 4 results,  Open Access: 3 results,  Acknowledgement Compliant: 4 results) Presentation (6 results) (of which Int'l Joint Research: 2 results,  Invited: 1 results) Book (2 results) Remarks (1 results)

  • [Journal Article] Pre-operative psoas muscle mass and post-operative gait speed following total hip arthroplasty for osteoarthritis.2016

    • Author(s)
      Wakabayashi H, Watanabe N, Anraku M, Oritsu H, Shimizu Y.
    • Journal Title

      J Cachexia Sarcopenia Muscle

      Volume: 7 Issue: 1 Pages: 95-96

    • DOI

      10.1002/jcsm.12046

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] 11. Rehabilitation Nutrition for Acute Heart Failure on Inotropes with Malnutrition, Sarcopenia, and Cachexia: A Case Report.2016

    • Author(s)
      Someya R, Wakabayashi H, Hayashi K, Akiyama E, Kimura K.
    • Journal Title

      J Acad Nutr Diet

      Volume: 116 Issue: 5 Pages: 765-768

    • DOI

      10.1016/j.jand.2015.11.002

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Skeletal muscle mass is associated with severe dysphagia in cancer patients.2015

    • Author(s)
      Wakabayashi H, Matsushima M, Uwano R, Watanabe N, Oritsu H, Shimizu Y.
    • Journal Title

      J Cachexia Sarcopenia Muscle

      Volume: 6 Issue: 4 Pages: 351-357

    • DOI

      10.1002/jcsm.12052

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Rehabilitation nutrition for sarcopenia with disability: a combination of both rehabilitation and nutrition care management2014

    • Author(s)
      Wakabayashi H, Sakuma K
    • Journal Title

      J Cachexia Sarcopenia Muscle

      Volume: 5 Issue: 4 Pages: 269-277

    • DOI

      10.1007/s13539-014-0162-x

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Presentation] Skeletal muscle mass is associated with severe dysphagia in cancer patients.2015

    • Author(s)
      Wakabayashi H
    • Organizer
      8th International Conference of the Society on Sarcopenia, Cachexia and Wasting Disorders
    • Place of Presentation
      Paris
    • Year and Date
      2015-12-04
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Sarcopenia, sarcopenic dysphagia, and rehabilitation nutrition2015

    • Author(s)
      Sarcopenia, sarcopenic dysphagia, and rehabilitation nutrition
    • Organizer
      16th Congress of Parenteral and Enteral Nutrition Society of Asia
    • Place of Presentation
      Nagoya
    • Year and Date
      2015-07-24
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 摂食嚥下障害のある癌患者の大腰筋筋肉量・ADLと経口摂取2015

    • Author(s)
      若林秀隆
    • Organizer
      第52回日本リハビリテーション医学会学術集会
    • Place of Presentation
      新潟
    • Year and Date
      2015-05-28
    • Related Report
      2015 Annual Research Report
  • [Presentation] 人工股関節置換術を施行した変形性股関節症患者の前サルコペニアおよび前サルコペニア肥満の実態2015

    • Author(s)
      若林秀隆
    • Organizer
      第18回日本病態栄養学会
    • Place of Presentation
      京都
    • Year and Date
      2015-01-10 – 2015-01-11
    • Related Report
      2014 Research-status Report
  • [Presentation] Association between dysphagia assessed by the 10-item eating assessment tool (EAT-10) and malnutrition in frail elderly2014

    • Author(s)
      Wakabayashi H
    • Organizer
      36th Congress of the European Society of Clinical Nutrition and Metabolism
    • Place of Presentation
      Geneva
    • Year and Date
      2014-09-06 – 2014-09-09
    • Related Report
      2014 Research-status Report
  • [Presentation] Association between muscle strength of head lifting, dysphagia, and malnutrition in Japanese elderly: possibility of sarcopenic dysphagia2013

    • Author(s)
      Hidetaka Wakabayashi
    • Organizer
      7th international meeting of the Society on Sarcopenia, Cachexia and Wasting Disease
    • Place of Presentation
      Kobe
    • Related Report
      2013 Research-status Report
  • [Book] 悪液質とサルコペニア-リハビリテーション栄養アプローチ2014

    • Author(s)
      荒金英樹、若林秀隆
    • Total Pages
      184
    • Publisher
      医歯薬出版
    • Related Report
      2013 Research-status Report
  • [Book] 高齢者リハビリテーション栄養2013

    • Author(s)
      若林秀隆
    • Total Pages
      139
    • Publisher
      カイ書林
    • Related Report
      2013 Research-status Report
  • [Remarks] リハビリテーション栄養・サルコペニア

    • URL

      http://rehabnutrition.blogspot.jp/

    • Related Report
      2013 Research-status Report

URL: 

Published: 2014-07-25   Modified: 2019-07-29  

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