| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Outline of Final Research Achievements |
In the present study, we developed a new experimental model using decerebrated and arterially perfused rat preparations to investigate neuronal mechanisms generating suckling and chewing. We first observed respiratory conditions in the preparations. As a result, the activity of the upper airway muscles in hypercapnic acidosis differs from that under normocapnic conditions. We next tried induction of suckling and chewing rhythms by electrical stimulation of the hard palate or application of NMDA. The rhythmic activity was induced by electrical stimulation or NMDA application in the masseter nerve and the mylohyoid nerve alternatively.
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