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Oxygenation state of the frontal lobe and lower limb muscles during the 6-min walk test in healthy old subjects and patients with COPD.

Research Project

Project/Area Number 25350624
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Rehabilitation science/Welfare engineering
Research InstitutionTokai University

Principal Investigator

KUTSUZAWA Tomoko  東海大学, 健康科学部, 教授 (10183310)

Co-Investigator(Renkei-kenkyūsha) KURITA Daisaku  東海大学, 情報教育センター, 准教授 (10547970)
WAKABAYASHI Ritsuko  東海大学, 健康科学部, 准教授 (20609359)
Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2015: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2014: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2013: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Keywords6分間歩行試験 / 近赤外分光法 / 慢性閉塞性肺疾患 / 高齢者 / 腓腹筋 / 外側広筋 / 前頭葉 / 酸素化状態 / COPD / 6分間歩行試験 / 下肢筋 / 独立成分分析 / 健常高齢者 / 筋肉酸素化状態 / 経皮酸素飽和度
Outline of Final Research Achievements

We measured the oxygenation state of the lower limb muscles and frontal lobe during the 6-min walk test (6MWT) in patients with COPD and healthy elderly subjects using a mobile near infrared spectroscopy (NIRS) device. The kinetics of total hemoglobin and oxygenated hemoglobin (HbO2) of gastrocnemius muscle during the 6MWT may be different from that of vastus lateralis muscle in the healthy elderly men. COPD patients showed that an amount of increase in HbO2 in the gastrocnemius muscle during the 6MWT tended to be attenuated. In addition, the oxygenation of the gastrocnemius muscle may influence the SpO2 in COPD patients with hypoxemia during the 6MWT.  The frontal lobe may not be activated during the 6MWT because the oxygenation of frontal lobe, which was analyzed by independent component analysis, did not increase.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report

Research Products

(5 results)

All 2016 2015 2014 Other

All Presentation (5 results) (of which Int'l Joint Research: 1 results)

  • [Presentation] 健常高齢者の6分間歩行試験中の前頭葉酸素化状態・・顔面血液量変化の除去の試み2016

    • Author(s)
      沓澤 智子、栗田 太作、池内 眞弓、灰田 宗孝
    • Organizer
      第56回日本呼吸器学会学術講演会
    • Place of Presentation
      国立京都国際会館(京都府京都市左京区宝ヶ池)
    • Year and Date
      2016-04-08
    • Related Report
      2015 Annual Research Report
  • [Presentation] Oxygenation state of the calf muscle during the 6-min walk test in patients with COPD2015

    • Author(s)
      Tomoko Kutsuzawa, Daisaku Kurita, Mayumi Ikeuchi
    • Organizer
      European Respiratory Society 2015 International Congress
    • Place of Presentation
      RAI アムステルダム、アムステルダム、オランダ
    • Year and Date
      2015-09-26
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] COPD患者における6分間歩行中の下肢筋の酸素化状態2015

    • Author(s)
      沓澤智子、栗田太作、池内眞弓、若林律子、灰田宗孝
    • Organizer
      第55回日本呼吸器学会学術講演会
    • Place of Presentation
      東京国際フォーラム
    • Year and Date
      2015-04-17 – 2015-04-19
    • Related Report
      2014 Research-status Report
  • [Presentation] 若者と中高年における6分間歩行中の下肢筋の酸素化状態2014

    • Author(s)
      沓澤智子、若林律子、池内眞弓、栗田太作、灰田宗孝
    • Organizer
      第24回日本呼吸ケア・リハビリテーション学会学術集会
    • Place of Presentation
      ホテル日航奈良
    • Year and Date
      2014-10-24 – 2014-10-25
    • Related Report
      2014 Research-status Report
  • [Presentation] 健常高齢者における6分間歩行運動中の腓腹筋および外側広筋の酸素化状態

    • Author(s)
      沓澤 智子、栗田太作、池内眞弓、若林律子、灰田宗孝
    • Organizer
      第54回日本呼吸器学会学術講演会
    • Place of Presentation
      大阪国際会議場
    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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