Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2015: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2013: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
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Outline of Final Research Achievements |
Reciprocal inhibition of antagonist muscles is crucial for motor learning in humans. Reward probability differentially altered behavioral probability and corticospinal excitability for reciprocal muscles, including the reward-related circuit. In addition, paired associative stimulation (PAS) is used to induce plasticity in the human motor cortex. Although reciprocal inhibition of antagonist muscles plays a fundamental role in human movements, (a) change in cortical circuits for reciprocal muscles by reward probability and (b) change in cortical circuits for reciprocal muscles by PAS are unknown. The results of this study implied that (a) reward probability differentially altered behavioral probability and corticospinal excitability for reciprocal muscles and (b) the cortical excitability for antagonist muscle within M1 decreased by PAS.
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