Behavioral training based on the reward and paired associative stimulation: improvement of reciprocal inhibition dysfunction
Project/Area Number |
25350632
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Rehabilitation science/Welfare engineering
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Research Institution | Kitasato University |
Principal Investigator |
SUZUKI Makoto 北里大学, 医療衛生学部, 教授 (80554302)
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Co-Investigator(Kenkyū-buntansha) |
KIRIMOTO Hikari 新潟医療福祉大学, 医療技術学部, 教授 (40406260)
ONISHI Hideaki 新潟医療福祉大学, 医療技術学部, 教授 (90339953)
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Project Period (FY) |
2013-04-01 – 2016-03-31
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Project Status |
Completed (Fiscal Year 2015)
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Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2015: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2013: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
|
Keywords | 運動学習 / 経頭蓋磁気刺激 / 行動学習 |
Outline of Final Research Achievements |
Reciprocal inhibition of antagonist muscles is crucial for motor learning in humans. Reward probability differentially altered behavioral probability and corticospinal excitability for reciprocal muscles, including the reward-related circuit. In addition, paired associative stimulation (PAS) is used to induce plasticity in the human motor cortex. Although reciprocal inhibition of antagonist muscles plays a fundamental role in human movements, (a) change in cortical circuits for reciprocal muscles by reward probability and (b) change in cortical circuits for reciprocal muscles by PAS are unknown. The results of this study implied that (a) reward probability differentially altered behavioral probability and corticospinal excitability for reciprocal muscles and (b) the cortical excitability for antagonist muscle within M1 decreased by PAS.
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Report
(4 results)
Research Products
(45 results)
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[Presentation] Induction of intracortical plasticity for reciprocal muscles by paired associative stimulation2014
Author(s)
Makoto Watanabe, Makoto Suzuki, Kazuhiro Sugawara, Takayuki Kawaguchi, Kayoko Takahashi, Shinobu Shimizu, Atsuhiko Matsunaga, Michinari Fukuda, Hideaki Onishi
Organizer
9th Form of Neuroscience on Federation of European Neuroscience Societies
Place of Presentation
Milano C ongressi, Milan, Italy
Year and Date
2014-07-05 – 2014-07-09
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[Presentation] The effect of anodal transcrinial direct current stimulation to the sensorimotor cortex on somatosensory evoked magnetic fields2013
Author(s)
Kazuhiro Sugawara, Hideaki Onishi, Koya Yamashiro, Sho Kojima, Shota Miyaguchi, Atsuhiro Tsubaki, Makoto Suzuki, Hikari Kirimoto, Hiroyuki Tamaki, Hiroatsu Murakami, Shigeki Kameyama
Organizer
World Congress of Neurology
Place of Presentation
Messe Wien Exhibition & Congress Center (Austria)
Related Report
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