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Perioperative nutritional intervention combined with therapeutic exercise in gastric cancer patients to prevent complications after gastric surgery

Research Project

Project/Area Number 25350635
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Rehabilitation science/Welfare engineering
Research InstitutionAsahi University

Principal Investigator

KUME MAKOTO  朝日大学, 歯学部, 教授 (00372326)

Co-Investigator(Kenkyū-buntansha) KAWABE Atsushi  朝日大学, 歯学部, 准教授 (00350877)
NAKAJIMA Sanae  朝日大学, 歯学部, 准教授 (80387472)
Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2015: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2014: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2013: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Keywords栄養強化療法 / 内部障害リハビリテーション / 手術前後治療 / チーム医療 / 胃がん / リハビリテーション栄養 / 内部障害のリハビリテーション / 周術期栄養評価 / 多職種チーム医療 / がんのリハビリテーション
Outline of Final Research Achievements

Gastric cancer patients have multiple risk factors for malnutrition due to the neoplasm and the surgical stress. The aim of this study was to determine the effect of nutritional intervention combined with therapeutic exercise on the postoperative course of gastric cancer patients. Patients in group A received preoperative intervention (IMPACT) and walking exercise. Patients in group B were not supported by any nutritional agents and exercise before operation. In group A, TTR (rapid turnover protein, a nutritional parameter) was significantly increased after the nutritional intervention. Rate of postoperative complication (the Clavien-Dindo Classification) was significantly lower in group A than in group B. The length of post-operative stay was short in group A, but there were no significant differences between the groups statistically. Preoperative nutritional intervention and exercise for gastric cancer patients would be beneficial to prevent postoperative complications.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (7 results)

All 2016 2015 2014 Other

All Presentation (7 results) (of which Int'l Joint Research: 2 results)

  • [Presentation] 低栄養消化器癌患者に対する術前栄養介入の効果2016

    • Author(s)
      安江裕香、高橋貞子、青木百合子、小島孝雄、久米真
    • Organizer
      第31回日本静脈経腸栄養学会
    • Place of Presentation
      福岡
    • Year and Date
      2016-02-25
    • Related Report
      2015 Annual Research Report
  • [Presentation] The benefit of preoperative nutritional intervention in gastric cancer patients at risk of malnutrition to prevent complications after gastric surgery.2015

    • Author(s)
      Yasue Y, Takahashi S, Aoki Y, Nakajima Y, Kojima T, Takahashi Y, Ikeda A, Nakajima S, Kawabe A, Kume M.
    • Organizer
      The 16th PENSA (Parenteral and Enteral Nutrition Society of Asia)
    • Place of Presentation
      Nagoya
    • Year and Date
      2015-06-24
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Preoperative low value in body fat mass is a risk factor for surgical site infection related to digestive Surgery.2015

    • Author(s)
      Kume M
    • Organizer
      The 16th PENSA (Parenteral and Enteral Nutrition Society of Asia)
    • Place of Presentation
      Nagoya
    • Year and Date
      2015-06-24
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 高齢大腸癌患者の術前筋肉量とTTRが術後経過に与える負の影響について2015

    • Author(s)
      安江裕香
    • Organizer
      第30回日本静脈経腸栄養学会
    • Place of Presentation
      神戸
    • Year and Date
      2015-02-13
    • Related Report
      2014 Research-status Report
  • [Presentation] 高齢・胃がん患者の周術期栄養学的特徴2014

    • Author(s)
      久米真
    • Organizer
      第76回日本臨床外科学会総会
    • Place of Presentation
      郡山
    • Year and Date
      2014-11-22
    • Related Report
      2014 Research-status Report
  • [Presentation] 栄養と運動処方をバランスさせた胃がん周術期のリハビリテーション2014

    • Author(s)
      久米真
    • Organizer
      第51回日本リハビリテーション医学会学術集会
    • Place of Presentation
      名古屋
    • Year and Date
      2014-06-05
    • Related Report
      2014 Research-status Report
  • [Presentation] 消化器癌患者の周術期サルコペニアと栄養指標との関連について

    • Author(s)
      安江裕香、高橋貞子、青木百合、小島孝雄、久米真
    • Organizer
      第29回日本静脈経腸栄養学会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市西区みなとみらい)
    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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