The influence of Metabolic function and therapeutic evaluation for spastic hypertonia after central nerveous system injury
| Project/Area Number |
25350647
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Rehabilitation science/Welfare engineering
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| Research Institution | Kinki University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
KATO Amami 近畿大学, 医学部, 教授 (00233776)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2015: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2014: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2013: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
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| Keywords | 痙縮 / 代謝 / 治療 / 安静時代謝 / ITB療法 |
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| Outline of Final Research Achievements |
We realized that patients with spasticity or dystonia exhibit hypermetabolism due to spastic hypertonia, and investigated to what extent improvement of spastic hypertonia as a result of treatment affects metabolic function by measuring resting metabolism using a respiratory gas analyzer. All 20 patients for whom resting metabolism was measured exhibited resting hypermetabolism before the procedure, which declined in all patients after the procedure. This reduction was particularly marked in the 4 patients with dystonia and the 2 patients with spastic cerebral palsy, for whom resting metabolic rate measured before surgery was over 1.7 times the standardized value.Metabolic function also tended to correlate with improvements in Ashworth score, and we considered that metabolic function should be utilized in adjusting ITB treatment after the procedure
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Report
(4 results)
Research Products
(11 results)
