| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Outline of Final Research Achievements |
In sports and traumatology medicine, skeletal muscle injuries are common. However, we have not established the most optimal treatment for muscle injuries yet. Recently, we designed a novel transcutaneous CO2 application system using 100% CO2 gas, a transcutaneous CO2 absorption-enhancing hydrogel. In this study, we investigated the effects of transcutaneous CO2 application for injured tibialis anterior muscle in rat.
We investigate histologically injured muscle with or without CO2 absorption. The CO2 group accelerate muscle healing. In addition, from immunostaining and realtime PCR experiments, neo-vascular factor and muscle synthesis factors were also upregulated by CO2 absorption. This study may imply that a transcutaneous CO2 application can bring a therapeutic breakthrough for promotion of injured muscle repair.
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