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Development of an osteoporosis prevention program involving lipid metabolism disorder correction in postmenopausal women

Research Project

Project/Area Number 25350849
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Applied health science
Research InstitutionOkayama Prefectural University

Principal Investigator

KUBOTA MEGUMI  岡山県立大学, 保健福祉学部, 教授 (80254564)

Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords閉経 / 女性 / 脂質代謝 / 骨密度 / 骨粗鬆症 / 地域高齢女性
Outline of Final Research Achievements

The purpose of this study was to develop a osteoporosis prevention program to prevent the deterioration of dyslipidemia or arteriosclerosis and a decrease in the bone mineral density, contributing to the improvement of metabolic syndrome. Female rats were divided into the following groups:①SDT/OVX/high-fat diet、②SDT/OVX/ standard diet、③SD/OVX/ high-fat diet、④SD/OVX/ standard diet. I analyzed bone density, blood lipid, adiponectin, leptin and osteocalcin level. The increase in serum lipid concentration of the obese model rat was controlled menopause by an intake of the soy isoflavone. In addition, the suppressant effect of the drop of the bone density was accepted, too.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (7 results)

All 2016 2015

All Presentation (3 results) (of which Int'l Joint Research: 2 results) Book (4 results)

  • [Presentation] Evaluation of the effects of body fat and leptin on changes in the bone density of Japanese woman2015

    • Author(s)
      久保田恵
    • Organizer
      第12回アジア栄養学会議
    • Place of Presentation
      横浜
    • Year and Date
      2015-05-14 – 2015-05-18
    • Related Report
      2014 Research-status Report
  • [Presentation] Evaluation of the effects of body fat and leptin on changes in the bone density of Japanese woman2015

    • Author(s)
      Megumi Kubota  Rikako Inoue
    • Organizer
      ACN2015
    • Place of Presentation
      横浜
    • Year and Date
      2015-05-14
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Effect of Fermented Vegetable Food "OM-X" on Defecation Among Women2015

    • Author(s)
      Rikako Inoue Megumi Kubota
    • Organizer
      ACN2015
    • Place of Presentation
      横浜
    • Year and Date
      2015-05-14
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Book] 栄養科学シリーズNEXT応用栄養学(第5版)2016

    • Author(s)
      久保田恵
    • Total Pages
      20
    • Publisher
      講談社
    • Related Report
      2015 Annual Research Report
  • [Book] 栄養科学シリーズNEXT応用栄養学(第4版)2015

    • Author(s)
      久保田恵
    • Total Pages
      20
    • Publisher
      講談社
    • Related Report
      2015 Annual Research Report
  • [Book] 食事摂取基準 理論と応用2015

    • Author(s)
      久保田恵
    • Total Pages
      13
    • Publisher
      医歯薬出版
    • Related Report
      2015 Annual Research Report
  • [Book] NEXT応用栄養2015

    • Author(s)
      久保田恵
    • Total Pages
      254
    • Publisher
      講談社サイエンティフィック
    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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