| Project/Area Number |
25350855
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Applied health science
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| Research Institution | Tokai University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
ISHII Naoaki 東海大学, 医学部, 教授 (60096196)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 筋肉過少 / 内臓脂肪 / メタボリック症候群 / 生活習慣病 / 脂肪肝 / 隠れ肥満 / 動脈硬化 / ホモシステイン / コレステロール / 加齢性変化 |
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| Outline of Final Research Achievements |
Normal BMI with higher body fat is so-called “kakure-himan” as the same meaning of normal weight obesity (NWO). In our study, body fat percentage (BFP) was measured using Impedance and DXA methods. Control group contains Normal BMI (18.5-24.9) with normal BFP (less than 20% in men and 25% in women). NWO group contains normal BMI with higher BFP (more than 20% in men and 25% in women). Obesity group contains Higher BMI (greater than 25.0) with higher BFP. Parameters associated with Met-S, lifestyle related diseases and arterial sclerosis were analyzed. NWO was recognized in 42% of men and in 60% of women, and percentages of the population were increased along to age. The serum levels of TG, FFA, UA, PWV were higher, while adiponectin was lower in NOW in contrst with control but some of that showed no difference between obesity group. These result suggest that kakure-himan, which could be a major risk for metabolic syndrome, lifestyle related diseases and arterial sclerosis.
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