Aging related progression of Kakurehiman(normal weight obesity) worsen subjects of Met-s and life style related diseases
| Project/Area Number |
25350855
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Applied health science
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| Research Institution | Tokai University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
ISHII Naoaki 東海大学, 医学部, 教授 (60096196)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 筋肉過少 / 内臓脂肪 / メタボリック症候群 / 生活習慣病 / 脂肪肝 / 隠れ肥満 / 動脈硬化 / ホモシステイン / コレステロール / 加齢性変化 |
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| Outline of Final Research Achievements |
Normal BMI with higher body fat is so-called “kakure-himan” as the same meaning of normal weight obesity (NWO). In our study, body fat percentage (BFP) was measured using Impedance and DXA methods. Control group contains Normal BMI (18.5-24.9) with normal BFP (less than 20% in men and 25% in women). NWO group contains normal BMI with higher BFP (more than 20% in men and 25% in women). Obesity group contains Higher BMI (greater than 25.0) with higher BFP. Parameters associated with Met-S, lifestyle related diseases and arterial sclerosis were analyzed. NWO was recognized in 42% of men and in 60% of women, and percentages of the population were increased along to age. The serum levels of TG, FFA, UA, PWV were higher, while adiponectin was lower in NOW in contrst with control but some of that showed no difference between obesity group. These result suggest that kakure-himan, which could be a major risk for metabolic syndrome, lifestyle related diseases and arterial sclerosis.
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Report
(4 results)
Research Products
(83 results)
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[Journal Article] Acute portal vein thrombosis due to chronic relapsing pancreatitis2014
Author(s)
Kikuchi M, Nishizaki Y, Tsuruya K, Hamada I, Higashi T, Sakuma K, Shiozawa H, Aoki J, Nagashima R, Koizumi J, Arase Y, Shiraishi K, Matsushima M, Mine T
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Journal Title
Clinical J Gastroenterology
Volume: 2014 (7)
Pages: 52-7
Related Report
Peer Reviewed / Open Access
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[Journal Article] 抗加齢ドック7年間の成果.2013
Author(s)
西崎泰弘. 山田千積, 茂出木成幸, 黒田恵美子, 桑平一郎, 谷野隆三郎, 久保明, 石井直明.
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Journal Title
日本老年医学会雑誌
Volume: 50(6)
Pages: 784-787
Related Report
Peer Reviewed
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[Presentation] Utility of quantitative controlled attenuation parameter to diagnose alcoholic liver disease2016
Author(s)
Kikuchi M, Nishizaki Y, Umeda R, Tsuruya K, Shiozawa H, Kinoshita S, Takabayashi K, Kato M, Kikuchi M, Fujiyama Y, Uraoka T, Horie Y, Kanai T
Organizer
25th Asian Pacific Association for the Study of the Liver
Place of Presentation
Tokyo (Japan)
Year and Date
2016-02-01
Related Report
Int'l Joint Research
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[Presentation] 抗加齢ドック受診者におけるオプテイマルヘルスからみた隠れ肥満～指導最適化における体脂肪率の在り方について2014
Author(s)
西崎泰弘, 山田千積, 岸本憲明, 久保明, 黒田恵美子, 茂出木茂幸, 尾形珠恵 , 竹田麻美 , 桑平一郎 , 谷野隆三郎 , 石井直明
Organizer
第１４回日本抗加齢医学会総会
Place of Presentation
大阪
Year and Date
2014-06-06 – 2014-06-08
Related Report
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[Presentation] Utility of quantitative controlled attenuation parameter (CAP) to diagnose non-alcoholic fatty liver disease (NAFLD).2014
Author(s)
Kikuchi M, Nishizaki Y, Imoto A, Hamada I, Tsuruya K, Nakahara F, Shiozawa H, Aoki J, Matsushima M, Mine T.
Organizer
24th Asian Pacific Association for the Study of the Liver
Place of Presentation
Brisbane, Australia
Related Report
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