| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
|
|---|
| Outline of Final Research Achievements |
Upon serum deprivation, C2C12 culture contains two different subpopulation, multinucleated myotubes and undifferentiated reserve cells, like quiescent satellite cells. Using this cell culture system, we investigated the regulatory mechanism for the maintenance of functionality of reserve cells under nutrition starvation. Reserve cells exhibited more marked tolerance to nutrition starvation than myotubes. Reserve cells did not impair their ability to regulate cell proliferation and differentiation, suggesting the maintenance of their cell functionality.
|
