Spatiotemporal patterns in inferior temporal cortex during visual object recognition probing by wide area brain stimulation

• Project/Area Number: 25350997
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Brain biometrics
• Research Institution: Niigata University
• Principal Investigator: Kawasaki Keisuke 新潟大学, 医歯学系, 准教授 (60511178)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Project Status: Completed (Fiscal Year 2015)
• Budget Amount: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000); Fiscal Year 2015: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2014: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2013: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
• Keywords: brain stimulation / inferior temporal cortex / visual recognition / 視覚物体認識 / 多点脳刺激法 / 多点脳活動記録法 / カテゴリ認知 / 視覚認知 / 皮質脳波 / 神経科学

Outline of Final Research Achievements

The inferior temporal cortex (IT) of the monkey plays an essential role in visual object recognition. Neurons in IT encodes visual features for object identification such as shape, color and surface properties. It is still unclear how wide areal activity patterns of the IT contribute the recognition process. In this study we aimed 1) to identify the wide areal activity patterns underlying visual recognition 2) to identify the effect of the perturbation on spatiotemporal activity patterns of IT. We revealed that recognition memory representation emerged as shared spatial patterns of theta activity spanning the IT. We also reveal that the spatiotemporal activity patterns of the IT engaged information flow. The fast oscillation of feedforward and feedback flow was observed. The flow dynamics may reflects hierarchal neuronal information processing. We developed a multichannel simultaneous recording and stimulation system for wide area brain stimulation.

Research Products

• [Journal Article] Associative-memory representations emerge as shared spatial patterns of theta activity spanning the primate temporal cortex (2016)
  • Author(s): Kiyoshi Nakahara, Ken Adachi, Keisuke Kawasaki, Takeshi Matsuo, Hirohito Sawahata, Kei Majima, Masaki Takeda, Sayaka Sugiyama, Ryota Nakata, Atsuhiko Iijima, Hisashi Tanigawa, Takafumi Suzuki, Yukiyasu Kamitani and Isao Hasegawa
  • Journal Title: Nature Communications Volume: in press
  • NAID: 120005822769
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Alternating zones selective to faces and written words in the human ventral occipitotemporal cortex (2013)
  • Author(s): Matsuo T, Kawasaki K, Kawai K, Majima K, Masuda H, Murakami H, Kunii N, Kamitani Y, Kameyama S, Saito N, Hasegawa I
  • Journal Title: Cereb Cortex Volume: (in press) Issue: 5 Pages: 1265-77
  • DOI: 10.1093/cercor/bht319
  • Peer Reviewed
• [Presentation] 皮質脳波法で見た下側頭葉皮質の階層的な視覚情報処理ネットワーク (2016)
  • Author(s): 川嵜 圭祐
  • Organizer: 第55回日本生体医工学会大会
  • Place of Presentation: 富山国際会議場（富山県・富山市）
  • Year and Date: 2016-04-26
• [Presentation] Information flow dynamics in inferior temporal cortex involving visual object processing (2015)
  • Author(s): Kawasaki K, Haruna T, Sawahata H, Tanigawa H, Iijima A, Suzuki T, Hasegawa I.
  • Organizer: Society for 2015
  • Place of Presentation: Cicago, USA
  • Year and Date: 2015-10-17
  • Int'l Joint Research
• [Presentation] Tanigawa H, Takei R, Majima K, Kawasaki K, Suzuki T, Nakahara K, Kamitani Y, Hasegawa I. Decording from ECoG signals reveals the contents of color imagery in macaque inferior temporal and prefrontal cortices (2015)
  • Author(s): Tanigawa H, Takei R, Majima K, Kawasaki K, Suzuki T, Nakahara K, Kamitani Y, Hasegawa I
  • Organizer: The 6th FAONS congress and the 11th Biennial conference of CNS
  • Place of Presentation: Wuzhen, ChIna
  • Year and Date: 2015-09-20
  • Int'l Joint Research
• [Presentation] サルの下側頭皮質と前頭前皮質からの皮質脳波を用いた色イメージ情報の解読 (2015)
  • Author(s): 谷川 久, 武井 廉, 間島 慶, 川嵜 圭祐, 澤畑 博人, 中原 潔, 鈴木 隆文, 神谷 之康, 長谷川 功.
  • Organizer: 第25回日本神経回路学会全国大会 (JNNS2015)
  • Place of Presentation: 電気通信大学（東京都・調布市）
  • Year and Date: 2015-09-02
• [Presentation] 連合学習に伴うサル内側側頭皮質脳波の 周波数間結合の増大 (2015)
  • Author(s): 中田 涼太, 安達 賢, 川嵜 圭祐, 澤畑 博人, 松尾 健, 鈴木 隆文, 谷川 久, 飯島 敦彦, 長谷川 功, 中原 潔
  • Organizer: 第38回日本神経科学大会
  • Place of Presentation: 神戸国際会議場（兵庫県・神戸市）
  • Year and Date: 2015-07-28
• [Presentation] マカクザルの前頭前皮質における図形文字処理に関わる脳内メカニズム (2015)
  • Author(s): 宮島 友章, 飯島 敦彦, 川嵜 圭祐, 谷川 久, 澤畑 博人, 鈴木 隆文, 松尾 健, 長谷川 功
  • Organizer: 第38回日本神経科学大会
  • Place of Presentation: 神戸国際会議場（兵庫県・神戸市）
  • Year and Date: 2015-07-28
• [Presentation] Hierarchical propagation of visual response through the inferior temporal cortex (2014)
  • Author(s): K. KAWASAKI, T. HARUNA, Y. FUJIKI, H. SAWAHATA, H. TANIGAWA, A. IIJIMA, T. SUZUKI, I. HASEGAWA
  • Organizer: 日本神経科学大会
  • Place of Presentation: 横浜
  • Year and Date: 2014-09-13
• [Presentation] Cortical theta wave associated with visual long-term memory in the monkey medial temporal lobe
  • Author(s): Adachi K., Kawasaki K., Sawahata H., Matsuo T., Suzuki T., Tanigawa H., Iijima I., Hasegawa I., Nakahara K.
  • Organizer: Neuroscience 2013
  • Place of Presentation: San diego, USA
• [Presentation] Decoding recalled visual memory using electrocorticographic (ECoG) signals in macaque inferior temporal and prefrontal cortices
  • Author(s): Tanigawa H., Majima K., Kawasaki K., Sawahata H., Nakahara K., Suzuki T., Kamitani Y., Hasegawa I.
  • Organizer: Neuro 2013
  • Place of Presentation: Kyoto, Japan
• [Presentation] Cross-frequency coupling of cortical oscillations during long-term memory retrieval in the monkey medial temporal lobe
  • Author(s): Adachi K., Kawasaki K., Sawahata H., Matsuo T., Suzuki T., Tanigawa H., Iijima I., Hasegawa I., Nakahara K.
  • Organizer: Neuro 2013
  • Place of Presentation: Kyoto, Japan
• [Presentation] マカクザル下側頭葉皮質視覚情報処理における整流作用:順列局所伝達エントロピー解析
  • Author(s): 藤木裕也, 春名太一, 川嵜圭祐, 澤畑博人, 鈴木隆文, 長谷川功
  • Organizer: 第14回計測自動制御学会
  • Place of Presentation: 神戸