Development and validation of the real-time quantification of cerebral blood flow using an arterial spin labeling MRI
| Project/Area Number |
25351003
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Brain biometrics
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| Research Institution | National Institute of Information and Communications Technology |
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Principal Investigator |
Toyoda Hiroshi 国立研究開発法人情報通信研究機構, 脳情報通信融合研究センター脳情報通信融合研究室, 主任研究員 (10558084)
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| Project Period (FY) |
2013-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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| Keywords | MRI / 脳血流量 / 動脈スピン標識法 |
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| Outline of Final Research Achievements |
We have developed a novel real-time measurement technique for quantitating cerebral blood flow using an arterial spin labeling method. Compared to the BOLD signal measurement, which is commonly used as a functional MRI method, the arterial spin labeling method generally requires more measurement time to image whole brain functions. In this study, high-speed MR imaging of cerebral blood flow was conducted by applying a parallel imaging technique to the arterial spin labeling method. To parallelize the imaging, we used a simultaneous multi-slice imaging technique with multi-band excitation RF pulses. Because it is less prone to magnetic susceptibility artifacts, the proposed imaging method may be used to investigate areas in the brain that were difficult to image using conventional BOLD functional MRI techniques.
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Report
(5 results)
Research Products
(16 results)
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[Journal Article] A voxel-based analysis of brain activity in high-order trigeminal pathway in the rat induced by cortical spreading depression.2015
Author(s)
Cui, Y., Toyoda, H., Sako, T., Onoe, K., Hayashinaka, E., Wada, Y., Yokoyama, C., Onoe, H., Kataoka, Y., and Watanabe, Y.
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Journal Title
NeuroImage
Volume: 108
Pages: 17-22
DOI
Related Report
Peer Reviewed / Open Access
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[Presentation] Migraine pathophysiology studied with small-animal PET2014
Author(s)
Yilong Cui, Hiroshi Toyoda, Takeo Sako, Kayo Onoe, Emi Hayashinaka, Yasuhiro Wada, Chihiro Yokoyama, Hirotaka Onoe, Yosky Kataoka, Yasuyoshi Watanabe
Organizer
The First CiNet Conference New Directions in Pain Neuroscience
Place of Presentation
Center for Information and Neural Networks, Osaka
Year and Date
2014-12-02
Related Report
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